Protein Alignment Sp1 and KLF17

DIOPT Version :9

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_775755.3
• Gene: KLF17 / 128209
• HGNCID: 18830
• Length: 389
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 114/421 - (27%)
• Similarity: 154/421 - (36%)
• Gaps: 110/421 - (26%)

  Fly   104 AGQHSPCAISAASSSSSSGSSGGQSS------------RSLSSSASTMVNITA------------ 144
            |.|.:..:....:.||||||||..:|            .|.....|.:|::.|
Human    25 AAQDNENSAPILNMSSSSGSSGVHTSWNQGLPSIQHFPHSAEMLGSPLVSVEAPGQNVNEGGPQF 89

  Fly   145 SRPLASSCAAVGGGSTGSSSSASGSQSSSTASAVAAAYGGDLYFPNTSTSNMDNHHMHQGLLGK- 208
            |.||.....:....:|.:.|.....|..|........:.|....|                :|:
Human    90 SMPLPERGMSYCPQATLTPSRMIYCQRMSPPQQEMTIFSGPQLMP----------------VGEP 138

  Fly   209 -VEAGAAAFGGVYSRHPYDWPFNAVTHKEAASVNSGWWDMHSAAGSWLDMGGAGMHSTMAN---- 268
             :...|..|||.....|...|.:|.|                         |..:.|...|
Human   139 NIPRVARPFGGNLRMPPNGLPVSAST-------------------------GIPIMSHTGNPPVP 178

  Fly   269 YASENYSSALSHSLLGSGQHLLQDTYKS------------MLPGQGVGVGVGVGMGGFSLPHSSP 321
            |.        ..|.:.|.:.||..|..|            |||.|...   .:||.    |..|.
Human   179 YP--------GLSTVPSDETLLGPTVPSTEAQAVLPSMAQMLPPQDAH---DLGMP----PAESQ 228

  Fly   322 SAAAAAAATAAAAAGGSPQGG-SPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIH 385
            |.....:..:..:...|.:|. .|..|.|..|       |.: .|.:..|..|..|  ..:...:
Human   229 SLLVLGSQDSLVSQPDSQEGPFLPEQPGPAPQ-------TVE-KNSRPQEGTGRRG--SSEARPY 283

  Fly   386 SCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVC 450
            .|:...|||.|.|.|||.:|.|.||||||:.|||..|...|.|||||:||:|.||..:.:.|..|
Human   284 CCNYENCGKAYTKRSHLVSHQRKHTGERPYSCNWESCSWSFFRSDELRRHMRVHTRYRPYKCDQC 348

  Fly   451 NKRFMRSDHLAKHVKTHN-GTANHQANGHNG 480
            ::.|||||||.:|.|||. |.::.|||.:||
Human   349 SREFMRSDHLKQHQKTHRPGPSDPQANNNNG 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	10/18 (56%)
		zf-H2C2_2	401..428	CDD:290200	15/26 (58%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:290200	9/22 (41%)
		zf-C2H2	445..467	CDD:278523	11/21 (52%)
		C2H2 Zn finger	447..467	CDD:275368	11/19 (58%)
KLF17	NP_775755.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		10/22 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	239..279		11/49 (22%)
		COG5048	282..>350	CDD:227381	34/67 (51%)
		zf-C2H2	283..307	CDD:278523	11/23 (48%)
		C2H2 Zn finger	285..307	CDD:275368	11/21 (52%)
		zf-C2H2	313..337	CDD:278523	13/23 (57%)
		C2H2 Zn finger	315..337	CDD:275368	13/21 (62%)
		zf-H2C2_2	329..352	CDD:290200	9/22 (41%)
		zf-C2H2	343..365	CDD:278523	11/21 (52%)
		C2H2 Zn finger	345..365	CDD:275368	11/19 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	356..389		13/24 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910