Protein Alignment Sp1 and LOC1274581

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_061498702.1
• Gene: LOC1274581 / 1274581
• VectorBaseID: AGAMI1_009673
• Length: 1284
• Species: Anopheles gambiae
• Alignment Length: 560
• Identity: 163/560 - (29%)
• Similarity: 230/560 - (41%)
• Gaps: 171/560 - (30%)

  Fly    17 IPAMGMNISNIATHL----------QKPQVNP-----DHPSL---------------RGTPLAML 51
            ||.:| |:..|.|:.          .:||:||     .|..|               |....|:.
Mosquito   811 IPGIG-NVQVIPTNFMQPVQPQTAASQPQLNPVTQAGQHQQLQQQQQGMQQQHQQQQRAIVAALQ 874

  Fly    52 AAQCNKLSNKSPPPLADAAVGKGFHPWKKSPNS--PAAGSSGSSGGGGGGGGSSAGQHSPCAISA 114
            .|...:||:....|...|.     |..|:...|  ||...:|::...|....|:.|  :|..|.|
Mosquito   875 QATAQQLSSIKQDPSEPAK-----HLVKQESLSTQPATAGNGATLATGALFTSAVG--APAQIVA 932

  Fly   115 ASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCAAVGGGSTGSSSSASGSQSSSTASAVA 179
            .||.:.|....|..|.::..:|||....::::..::....||    ||.:.|:|:.:....:.||
Mosquito   933 VSSGAGSLGGLGIPSSTIPGAASTATTPSSTQVNSAKGDLVG----GSPNQATGNVNVGANARVA 993

  Fly   180 AAYGGDLYFPNTSTSNMDNHHMHQGLLGKVEAGAAAFGGVYSRHPYDWPFNAVTHKEAASVNSGW 244
            :..||             ...:.:|  |:..|||.|...:
Mosquito   994 SETGG-------------KRGVGKG--GRAGAGAGAATAI------------------------- 1018

  Fly   245 WDMHSAAGSWLDMGGAGMHSTMANYASENYSSALSHSLLGSGQHLLQDTYKSMLPGQGVGVGVGV 309
                  ||:   ..||||...:...|.:.....:             :|..:::.|:.
Mosquito  1019 ------AGA---KAGAGMGMELGTAAGKEEPGEM-------------ETETTIISGEK------- 1054

  Fly   310 GMGGFSLPHSSPSAAAAAAATAAAAAGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGP 374
                 ...|:.|...:|.          ....|:|        |:...|..|.|||| |.:..||
Mosquito  1055 -----RRRHTIPKVVSAT----------HTMNGTP--------RQRVRRVACTCPNC-EVKSSGP 1095

  Fly   375 AGVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTH 439
            ..    :|..|.||:.||.|||||||||:||||||||||||:|||..||||||||||||||.|||
Mosquito  1096 PD----RKRQHICHVSGCNKVYGKTSHLRAHLRWHTGERPFICNWGTCGKRFTRSDELQRHRRTH 1156

  Fly   440 TGEKRFACPVCNKRFMRSDHLAKHVKTHNG-TANHQANGHNGGLKKG--------------SSES 489
            ||||||.|..|||:|||||||:||::||.. ..:|.::|:   .|.|              .::.
Mosquito  1157 TGEKRFECVECNKKFMRSDHLSKHIRTHGKFKRDHDSDGY---YKSGDELTYEEEEIHEIDDTDY 1218

  Fly   490 CSDSEEAAN---QSGESNGLGG--------VGSGPQTGGA 518
            ..|.|:.|:   ||..|:..|.        :|| |.||.:
Mosquito  1219 KMDDEDDADLERQSHHSSTAGAYDADKKDDIGS-PHTGSS 1257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	66/337 (20%)
		C2H2 Zn finger	390..409	CDD:275368	15/18 (83%)
		zf-H2C2_2	401..428	CDD:463886	22/26 (85%)
		C2H2 Zn finger	417..439	CDD:275368	18/21 (86%)
		zf-H2C2_2	431..454	CDD:463886	18/22 (82%)
		zf-C2H2	445..467	CDD:395048	14/21 (67%)
		C2H2 Zn finger	447..467	CDD:275368	13/19 (68%)
LOC1274581	XP_061498702.1	None