DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp1 and Klf16

DIOPT Version :9

Sequence 1:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_510962.2	Gene:	Klf16 / 118445	MGIID:	2153049	Length:	251	Species:	Mus musculus

Alignment Length:	178	Identity:	81/178 - (45%)
Similarity:	94/178 - (52%)	Gaps:	40/178 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 PGQGVGVGVGVGMGGFSLPHSSPSAAAA------AAATAAAAAGG-SPQGGSPSTPSPRSQRRYA 356
            ||.|         |..:.||...::..|      ..||||:.||| ||...|.:..||.|
Mouse    66 PGPG---------GATAAPHLLAASILADLRGGPVVATAASTAGGTSPVSSSSAASSPSS----- 116

  Fly   357 GRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLF 421
            |||    |...::               |.|...||.|.|.|:||||:|||.|||||||.|:|..
Mouse   117 GRA----PGAAKS---------------HRCPFHGCAKAYYKSSHLKSHLRTHTGERPFACDWPG 162

  Fly   422 CGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTHNG 469
            |.|:|.|||||.||.|||||||||.||:|.|||.|||||.||.:.|.|
Mouse   163 CDKKFARSDELARHHRTHTGEKRFPCPLCTKRFTRSDHLTKHARRHPG 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	12/18 (67%)
		zf-H2C2_2	401..428	CDD:290200	18/26 (69%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:290200	17/22 (77%)
		zf-C2H2	445..467	CDD:278523	14/21 (67%)
		C2H2 Zn finger	447..467	CDD:275368	13/19 (68%)
Klf16	NP_510962.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..72		4/14 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..125		15/38 (39%)
		COG5048	124..>186	CDD:227381	40/76 (53%)
		C2H2 Zn finger	128..150	CDD:275368	13/21 (62%)
		zf-H2C2_2	142..169	CDD:290200	18/26 (69%)
		COG5048	<158..>231	CDD:227381	36/53 (68%)
		C2H2 Zn finger	158..180	CDD:275368	13/21 (62%)
		zf-H2C2_2	172..197	CDD:290200	19/24 (79%)
		C2H2 Zn finger	188..208	CDD:275368	13/19 (68%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..251		5/10 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910