Protein Alignment Sp1 and klf2b

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_571932.1
• Gene: klf2b / 117509
• ZFINID: ZDB-GENE-011109-2
• Length: 363
• Species: Danio rerio
• Alignment Length: 417
• Identity: 111/417 - (26%)
• Similarity: 145/417 - (34%)
• Gaps: 141/417 - (33%)

  Fly   132 LSSSASTMVN-----------ITASRPLASSCAAVGGGSTGSSSSASGSQSSSTASAVAAAYGGD 185
            |..|.||..|           |...:||.:||..:....  ::.:..|.:.....|...     |
Zfish     6 LLPSISTFANQKEKLWEDRWKIEEHKPLNASCPPLNVAL--NTDTCRGRKDDEDLSNYL-----D 63

  Fly   186 LYFPNTSTSNMDNHHMHQGLLGKVEAGAAAFG-----GVYSRHPYDW-----PFNAVTHKEAASV 240
            |.|...:|:            |.:||||....     |:||...|..     |:..:.....:.|
Zfish    64 LEFILANTT------------GPLEAGAEFISHSEPCGMYSTAVYSSPEAPPPYGLMAELLRSDV 116

  Fly   241 NSGWWDMHSAAGSWL------------------DMGGAG-----MHSTMANYASE-NYSSALSHS 281
            :| .:|. :..|.:|                  .|.|.|     :..|......| |.|..:|..
Zfish   117 DS-TYDT-TVQGRFLLNSSGFPRQEFPEIKVEPPMDGYGPVIGMVPQTCQKIKQEGNVSCMMSFE 179

  Fly   282 -----------------LLGSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPS------- 322
                             |.....||.|.||..                  |..||.|:
Zfish   180 QPRLAVSPQATGNMTPPLSPDDSHLRQTTYTQ------------------SYHHSPPAYPQVPMQ 226

  Fly   323 -AAAAAAATAAAAAGGSPQG-----GSPSTP------SPRSQRRYAGRATCDCPNCQEAERLGPA 375
             .|....|....|.|..|..     ..||:|      .|:..||...|
Zfish   227 FTAPHQFAMYEEAMGMQPSMQRALLTPPSSPLELMESKPKRGRRTWPR----------------- 274

  Fly   376 GVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHT 440
                ::...|:|...||||.|.|:||||||.|.||||:|:.|||..||.:|.|||||.||.|.||
Zfish   275 ----KRMATHTCTYAGCGKTYTKSSHLKAHHRTHTGEKPYHCNWEGCGWKFARSDELTRHFRKHT 335

  Fly   441 GEKRFACPVCNKRFMRSDHLAKHVKTH 467
            |.:.|.|.:|.:.|.||||||.|:|.|
Zfish   336 GHRPFQCHLCERAFSRSDHLALHMKRH 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	61/334 (18%)
		C2H2 Zn finger	390..409	CDD:275368	13/18 (72%)
		zf-H2C2_2	401..428	CDD:463886	17/26 (65%)
		C2H2 Zn finger	417..439	CDD:275368	14/21 (67%)
		zf-H2C2_2	431..454	CDD:463886	11/22 (50%)
		zf-C2H2	445..467	CDD:395048	12/21 (57%)
		C2H2 Zn finger	447..467	CDD:275368	11/19 (58%)
klf2b	NP_571932.1	KLF2_N	5..280	CDD:409229	61/333 (18%)
		COG5048	<275..358	CDD:227381	47/82 (57%)
		C2H2 Zn finger	282..304	CDD:275368	14/21 (67%)
		C2H2 Zn finger	312..334	CDD:275368	14/21 (67%)
		zf-H2C2_2	326..351	CDD:463886	12/24 (50%)
		C2H2 Zn finger	342..362	CDD:275368	11/19 (58%)