Protein Alignment Sp1 and sp7

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001128590.1
• Gene: sp7 / 100189548
• XenbaseID: XB-GENE-954330
• Length: 427
• Species: Xenopus tropicalis
• Alignment Length: 520
• Identity: 174/520 - (33%)
• Similarity: 220/520 - (42%)
• Gaps: 153/520 - (29%)

  Fly    46 TPLAMLAAQCNKLSNKSPPPLADAAVGKGFHPWKKSPNSPAAGSSGSSGGGGGG-----GGSSAG 105
            :|||||.|.|||....||...:.::...|.    |.|.|.....|.|...|.|.     |||:.
 Frog    15 SPLAMLTAACNKFGGSSPIRDSTSSSKSGV----KKPYSQTNEFSASKLMGDGYSSAYLGGSNI- 74

  Fly   106 QHSPCAISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCAAVGGGSTGSSSSASGSQ 170
             .:||....|  .|:.|...|..|.|.|                            |||.....:
 Frog    75 -MTPCGTPPA--PSNYGGDFGSFSHSFS----------------------------SSSGCQEPK 108

  Fly   171 SSSTASAVAAAYGGDLYFPNTSTSNMDNHHMHQGLLGKVEAGAAAFGGVYSRHPY-DWPFNAVTH 234
            |.|.|..|.:.|           :::|        :|               ||| .|....:.|
 Frog   109 SLSPAECVPSVY-----------TSLD--------MG---------------HPYGSWYKTGIHH 139

  Fly   235 KEAASVNSG----WWDMHSAAGSWL------------------DMGGAGMHS------TMANYAS 271
            ...:|...|    |||||... :||                  .:|.:..:|      |.|.|.|
 Frog   140 PSLSSSPPGSGGSWWDMHPNT-NWLGNQSQPDGLAASMPPVTSPVGMSSQYSAEYTTLTPATYPS 203

  Fly   272 ENYSSALSHSLLGSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAAAG 336
            ..:.|....|......|||..:..::.|..                 ..|...||
 Frog   204 VGFPSISPSSSPSPSSHLLSPSQHTLAPEM-----------------YKPKLLAA---------- 241

  Fly   337 GSPQGGSPSTPSPRSQRRY--AGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKT 399
             :|...:|.:...:....|  :||.:||||||||.||||.:...|::|.:||||||||||||||.
 Frog   242 -NPLLETPGSLKAQRGTSYGNSGRPSCDCPNCQELERLGASAASLKRKPVHSCHIPGCGKVYGKA 305

  Fly   400 SHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHV 464
            |||||||||||||||||||||||||||||||||:||:||||.||:|.||:|.|||.|||||:||.
 Frog   306 SHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCPLCAKRFTRSDHLSKHQ 370

  Fly   465 KTH---NGTANHQANGHNGGLKKGSSES---CSDSEEAANQSGESNGLGGVGSGPQTGGAGGGGG 523
            ::|   .|..:....|..|.:.:.|:|.   .|||..|.            ||..:..|:.|.||
 Frog   371 RSHVDQPGAKDDGVQGDGGAVGESSAEKGIVLSDSSPAG------------GSQERASGSPGQGG 423

  Fly   524  523
             Frog   424  423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	86/371 (23%)
		C2H2 Zn finger	390..409	CDD:275368	17/18 (94%)
		zf-H2C2_2	401..428	CDD:463886	26/26 (100%)
		C2H2 Zn finger	417..439	CDD:275368	19/21 (90%)
		zf-H2C2_2	431..454	CDD:463886	15/22 (68%)
		zf-C2H2	445..467	CDD:395048	14/21 (67%)
		C2H2 Zn finger	447..467	CDD:275368	13/19 (68%)
sp7	NP_001128590.1	SP6-9_N	2..292	CDD:425402	89/375 (24%)
		C2H2 Zn finger	296..315	CDD:275368	17/18 (94%)
		zf-H2C2_2	307..334	CDD:463886	26/26 (100%)
		C2H2 Zn finger	323..345	CDD:275368	19/21 (90%)
		zf-H2C2_2	337..362	CDD:463886	17/24 (71%)
		C2H2 Zn finger	353..373	CDD:275368	13/19 (68%)