DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btd and MOT3

DIOPT Version :9

Sequence 1:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_013786.1	Gene:	MOT3 / 855092	SGDID:	S000004674	Length:	490	Species:	Saccharomyces cerevisiae

Alignment Length:	437	Identity:	114/437 - (26%)
Similarity:	161/437 - (36%)	Gaps:	150/437 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 HLTQQQQQQQQQQQQQQQQQQQQQQPQQQQHDFL---------SAAALLSAPPSLSGSSSGS--- 112
            ||.|||||:||.||||.||||.|.|.|||||..|         .:.:|.|.|.:.:..||..
Yeast     6 HLQQQQQQRQQHQQQQHQQQQHQHQHQQQQHTILQNVSNTNNIGSDSLASQPFNTTTVSSNKDDV 70

  Fly   113 --SSGSSPLYGKPPMKL---ELPYPQASSTGTASPNSSIQSAPSSASVSPSIFPSPAQS-FASIS 171
              :||:..|    ||.|   :..||....|...|.|::: :|.::.|.||.:..:...| .::||
Yeast    71 MVNSGAREL----PMPLHQQQYIYPYYQYTSNNSNNNNV-TAGNNMSASPIVHNNSNNSNNSNIS 130

  Fly   172 ASPSTPTTTLAPPTTAAAGALAGSPTSSS---------------PSSSAASAAAAAAAAAAAAAD 221
            ||..|               :|.:.||::               |:.            ..|||:
Yeast   131 ASDYT---------------VANNSTSNNNNNNNNNNNNNNNIHPNQ------------FTAAAN 168

  Fly   222 LGAAAVASAAYGWNTAYSGLGPARSQFPY--AQYASDYY---------GNAVGMSSSAAWFSHQE 275
            :.:.|.|:|.|.:.||...:.....|:.:  |.|.|.||         .||....|:.:  ||..
Yeast   169 MNSNAAAAAYYSFPTANMPIPQQDQQYMFNPASYISHYYSAVNSNNNGNNAANNGSNNS--SHSA 231

  Fly   276 RLYQPW-------------------------SSQSYPGFNFDDIAFQTQLQRRSVRCTCPNCTNE 315
            ....|.                         :.|.:|....|.  ||.|||:.    ..||....
Yeast   232 PAPAPGPPHHHHHHSNTHNNLNNGGAVNTNNAPQHHPTIITDQ--FQFQLQQN----PSPNLNLN 290

  Fly   316 MS-----GLPP---------------------------------IVGPDERGRKQHICHIPGCER 342
            ::     .|||                                 :..|....:..|.|..  ||:
Yeast   291 INPAQPLHLPPGWKINTMPQPRPTTAPNHPPAPVPSSNPVASNLVPAPSSDHKYIHQCQF--CEK 353

  Fly   343 LYGKASHLKTHLRWHTGERPFLCLTCGKRFSRSDELQRHGR-THTNY 388
            .:.:.|.||.||..|:.:|.|||..|..|..|.|.|.:|.: .||||
Yeast   354 SFKRKSWLKRHLLSHSQQRHFLCPWCLSRQKRKDNLLQHMKLKHTNY 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	7/18 (39%)
		zf-H2C2_2	349..374	CDD:290200	11/24 (46%)
		C2H2 Zn finger	365..385	CDD:275368	7/20 (35%)
		zf-H2C2_2	377..402	CDD:290200	6/13 (46%)
		zf-C2H2	391..413	CDD:278523
		C2H2 Zn finger	393..413	CDD:275368
MOT3	NP_013786.1	COG5048	61..>413	CDD:227381	86/382 (23%)
		C2H2 Zn finger	348..368	CDD:275370	8/21 (38%)
		C2H2 Zn finger	376..394	CDD:275370	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I1388
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050