Protein Alignment btd and ACE2

DIOPT Version :9

• Sequence 1: NP_511100.1
• Gene: btd / 31912
• FlyBaseID: FBgn0000233
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_013232.1
• Gene: ACE2 / 850822
• SGDID: S000004121
• Length: 770
• Species: Saccharomyces cerevisiae
• Alignment Length: 600
• Identity: 120/600 - (20%)
• Similarity: 190/600 - (31%)
• Gaps: 212/600 - (35%)

  Fly    10 NPYAQQHQAQQQQHAQHQQHAQQQQHHLHMQQAQHHLHLSHQQAQQQHMQHLTQQQQQQQQQQQQ 74
            |.|..|...:||:..:.....|::.:....:|      |...|.||:.::.:.::|::..|:...
Yeast   184 NSYLSQVLLKQQEELRIALEKQKEVNEKLEKQ------LRDNQIQQEKLRKVLEEQEEVAQKLVS 242

  Fly    75 QQQQQQQQ-------QQPQQQQHDFLSAAALLSA----------PP----------SLSGSSS-- 110
            .......:       :.|..|.......|.:::.          ||          |::||.|
Yeast   243 GATNSNSKPGSPVILKTPAMQNGRMKDNAIIVTTNSANGGYQFPPPTLISPRMSNTSINGSPSRK 307

  Fly   111 -------------------GSSSG---SSPLYGKPPMKLE-----LPYPQASSTGTASPNSSIQS 148
                               .|:||   .|.|....|....     |.|...::|...:.|....|
Yeast   308 YHRQRYPNKSPESNGLNLFSSNSGYLRDSELLSFSPQNYNLNLDGLTYNDHNNTSDKNNNDKKNS 372

  Fly   149 ------------APSSASVSPSIFPSPAQSFASISASPS----------TPTTTLAP-------- 183
                        :|...|:||.|..:..:|...:....|          ||.|.|:|
Yeast   373 TGDNIFRLFEKTSPGGLSISPRINGNSLRSPFLVGTDKSRDDRYAAGTFTPRTQLSPIHKKRESV 437

  Fly   184 ------------------------PTTAAAGALAGS------PTSSSPSSSAASAAAAAAAAAAA 218
                                    ||...|.|||.|      |.||:
Yeast   438 VSTVSTISQLQDDTEPIHMRNTQNPTLRNANALASSSVLPPIPGSSN------------------ 484

  Fly   219 AADLGAAAVASAAYGWNTAYSGLGPARSQFPYAQY-ASDYYG-NAVGMSSSAAWFSHQERLYQPW 281
                            ||......|.:..|.:... |....| |...:.::.....||..:..|.
Yeast   485 ----------------NTPIKNSLPQKHVFQHTPVKAPPKNGSNLAPLLNAPDLTDHQLEIKTPI 533

  Fly   282 SS------QSYPGFN--FDDIAFQTQLQRRS-------VRCTCPNCTNEMSGLPPIVG------- 324
            .:      :|||...  ..||.....|...|       .|.|....|.:.:.|||  |
Yeast   534 RNNSHCEVESYPQVPPVTHDIHKSPTLHSTSPLPDEIIPRTTPMKITKKPTTLPP--GTIDQYVK 596

  Fly   325 --PDERGRKQHICHIPGCERLYGKASHLKTHLRWHTGERPFLC--LTCGKRFSRSDELQRHGRTH 385
              ||    |...|..|.|.:::.:..::::|::.|..:||:.|  ..|.|.|.|:.:|.||..:|
Yeast   597 ELPD----KLFECLYPNCNKVFKRRYNIRSHIQTHLQDRPYSCDFPGCTKAFVRNHDLIRHKISH 657

  Fly   386 TNYRPYACPICSKKFSRSDHLSKHKKTHFKDKKSKKVLAAEAKEQAAAAIKLEKKEKKSGKPLTP 450
             |.:.|.|| |.|:|:|.|.|..|:         .:::....|          |.|....|.||.
Yeast   658 -NAKKYICP-CGKRFNREDALMVHR---------SRMICTGGK----------KLEHSINKKLTS 701

  Fly   451 PVEFKQEQP-DTTPL 464
            |.:...:.| ||:|:
Yeast   702 PKKSLLDSPHDTSPV 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	3/18 (17%)
		zf-H2C2_2	349..374	CDD:290200	8/26 (31%)
		C2H2 Zn finger	365..385	CDD:275368	8/21 (38%)
		zf-H2C2_2	377..402	CDD:290200	11/24 (46%)
		zf-C2H2	391..413	CDD:278523	10/21 (48%)
		C2H2 Zn finger	393..413	CDD:275368	9/19 (47%)
ACE2	NP_013232.1	COG5048	176..683	CDD:227381	109/555 (20%)
		C2H2 Zn finger	605..627	CDD:275368	4/21 (19%)
		C2H2 Zn finger	635..657	CDD:275368	8/21 (38%)
		C2H2 Zn finger	664..680	CDD:275368	8/16 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960