DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btd and sp3

DIOPT Version :9

Sequence 1:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	XP_002934651.1	Gene:	sp3 / 733736	XenbaseID:	XB-GENE-977158	Length:	750	Species:	Xenopus tropicalis

Alignment Length:	421	Identity:	129/421 - (30%)
Similarity:	180/421 - (42%)	Gaps:	86/421 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 HQQAQQQHMQH----LTQQQQ--QQQQQQQQQQQQQQQQQQPQQQQHDFLSAAALLSAPPSLSGS 108
            |.|....|..:    :|.:.|  |....|...||...|..||..|.....|.|.  .|..::.|.
Frog   320 HVQTSDLHGNYIQTSMTDESQNIQVSASQTMVQQIHLQDSQPTSQAQLVQSIAQ--QAIQAVQGG 382

  Fly   109 SSGSSSGSSPLYGKPPMKLELPYPQASSTGTASPNSSIQSAPSSASV-SPSIFPSPAQSFASISA 172
            :.|.||                        .|..|..:|..|.:..: :.::.||...::.:...
Frog   383 TQGLSS------------------------QALQNLQLQLNPGTFLIQAQTVTPSGQIAWQTFQV 423

  Fly   173 ------------SPSTPTTTLAPPTTAAAGALAGSPTSSSPSSSAASAAAAAAAAAAAAADLGAA 225
                        :.|....||.|..|...|.:||..|   |.|..|............:.|   |
Frog   424 QGVQNLQNLQIPNSSAQQITLTPVQTLTLGQVAGGGT---PVSLNAGQLPNLQTVTVNSVD---A 482

  Fly   226 AVASAAYGWNTAYSGLGPARSQFPYAQYASDYYGNAVGMSSSAAWFSHQERLYQPWSSQSYPGFN 290
            |.....:|.|        :.|......:.:..:.:::.:|:.......:|.....|........|
Frog   483 AGIHLHHGDN--------SDSPTEIETHQTRQHFSSLQLSNFGIRIKEEEPDPDEWQLAGDSTVN 539

  Fly   291 FDDIAF--------------QTQLQRRSVRCTCPNCTNEMSGLPPIVGPDERGRKQHICHIPGCE 341
            .:|:..              |...:.|.|.|||||| .:.:|....:|.    :||||||||||.
Frog   540 TNDLTHLRVQVVDDELDQPNQEGKRLRRVACTCPNC-KDGAGRGTNLGK----KKQHICHIPGCG 599

  Fly   342 RLYGKASHLKTHLRWHTGERPFLC--LTCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSD 404
            ::|||.|||:.|||||:|||||:|  :.|||||:||||||||.||||..:.:.||.|||:|.|||
Frog   600 KVYGKTSHLRAHLRWHSGERPFVCTWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSD 664

  Fly   405 HLSKHKKTHFKDKK----SKKVLAA-EAKEQ 430
            ||:||.||| ::||    |..|||: |||.:
Frog   665 HLAKHIKTH-QNKKGIHASSAVLASIEAKPE 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	12/18 (67%)
		zf-H2C2_2	349..374	CDD:290200	18/26 (69%)
		C2H2 Zn finger	365..385	CDD:275368	15/21 (71%)
		zf-H2C2_2	377..402	CDD:290200	15/24 (63%)
		zf-C2H2	391..413	CDD:278523	14/21 (67%)
		C2H2 Zn finger	393..413	CDD:275368	14/19 (74%)
sp3	XP_002934651.1	C2H2 Zn finger	593..615	CDD:275368	15/21 (71%)
		zf-H2C2_2	607..634	CDD:372612	18/26 (69%)
		C2H2 Zn finger	623..645	CDD:275368	15/21 (71%)
		zf-H2C2_2	637..660	CDD:372612	14/22 (64%)
		zf-C2H2	651..673	CDD:333835	14/21 (67%)
		C2H2 Zn finger	653..673	CDD:275368	14/19 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910