DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment btd and Sp5

DIOPT Version :9

Sequence 1:NP_511100.1 Gene:btd / 31912 FlyBaseID:FBgn0000233 Length:644 Species:Drosophila melanogaster
Sequence 2:NP_071880.1 Gene:Sp5 / 64406 MGIID:1927715 Length:398 Species:Mus musculus


Alignment Length:436 Identity:142/436 - (32%)
Similarity:188/436 - (43%) Gaps:149/436 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 QQQQQQQQPQQQQHDFLSAAALLSAPPSLSGSSSGSSSGS------SPLYGKP------------ 123
            |.:.....|...:|   |..|||:|..|..|....:::..      .|..|.|            
Mouse    17 QDRTPSASPDLGKH---SPLALLAATCSRIGQPGAAAAPDFLQVPYDPALGSPSRLFHPWTADMP 78

  Fly   124 ---PMKLELPYP-------------------QASSTGTASPN-----SSIQSAPSS-----ASVS 156
               |..|..|:|                   :...|..|.|:     |.::..|||     ||.:
Mouse    79 AHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCA 143

  Fly   157 PSIFPSPAQS-----FASISASPSTPTTTLAPPTTA------------------AAGALAGSPTS 198
            |:..|..||:     ::::...|..|    .||.|.                  .:||..||  |
Mouse   144 PAYVPYAAQAALPPGYSNLLPPPPPP----PPPPTCRQLSPAPAPDDLPWWSIPQSGAGPGS--S 202

  Fly   199 SSPSSSAASAA----------AAAAAAAAAAADLGAAAVASAAYGWNTAYSGLGPARSQFPYAQY 253
            ..|.:|.:||.          |:|||||||||.|....|             |||:    .:|||
Mouse   203 GVPGTSLSSACAGPPHAPRFPASAAAAAAAAAALQRGLV-------------LGPS----DFAQY 250

  Fly   254 ASDYYGNAVGMSSSAAWFSHQERLYQPWSSQSYPGFNFDDIAFQTQLQRRSVRCTCPNCTNEMSG 318
            .|..   |..:.:.|           |.::.:                ||..||.||||  :.:|
Mouse   251 QSQI---AALLQTKA-----------PLAATA----------------RRCRRCRCPNC--QAAG 283

  Fly   319 LPPIVGPDERGRKQHICHIPGCERLYGKASHLKTHLRWHTGERPFLC--LTCGKRFSRSDELQRH 381
            ..|...|.:  :|||:||:|||.::|||.||||.|||||||||||:|  |.|||.|:||||||||
Mouse   284 GAPEAEPGK--KKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRH 346

  Fly   382 GRTHTNYRPYACPICSKKFSRSDHLSKHKKTHFKDKKSKKVLAAEA 427
            .||||..:.:|||.|.|:|.|||||:||.|||    ::||:..|||
Mouse   347 LRTHTGEKRFACPECGKRFMRSDHLAKHVKTH----QNKKLKVAEA 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
btdNP_511100.1 C2H2 Zn finger 338..357 CDD:275368 13/18 (72%)
zf-H2C2_2 349..374 CDD:290200 20/26 (77%)
C2H2 Zn finger 365..385 CDD:275368 15/21 (71%)
zf-H2C2_2 377..402 CDD:290200 15/24 (63%)
zf-C2H2 391..413 CDD:278523 14/21 (67%)
C2H2 Zn finger 393..413 CDD:275368 13/19 (68%)
Sp5NP_071880.1 SP1-4_N 31..>47 CDD:425404 7/15 (47%)
SP5_N 106..297 CDD:412096 62/247 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 160..215 14/60 (23%)
9aaTAD. /evidence=ECO:0000250|UniProtKB:Q6BEB4 187..195 0/7 (0%)
C2H2 Zn finger 301..320 CDD:275368 13/18 (72%)
COG5048 <311..384 CDD:227381 51/76 (67%)
C2H2 Zn finger 328..350 CDD:275368 15/21 (71%)
zf-H2C2_2 342..365 CDD:404364 14/22 (64%)
C2H2 Zn finger 358..378 CDD:275368 13/19 (68%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3B9ZF
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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