DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment btd and KLF13

DIOPT Version :9

Sequence 1:NP_511100.1 Gene:btd / 31912 FlyBaseID:FBgn0000233 Length:644 Species:Drosophila melanogaster
Sequence 2:NP_057079.2 Gene:KLF13 / 51621 HGNCID:13672 Length:288 Species:Homo sapiens


Alignment Length:315 Identity:89/315 - (28%)
Similarity:116/315 - (36%) Gaps:135/315 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   142 PNSSIQSAPSSASV-----------------SPSIF---------------PSPAQSFASISASP 174
            |....:|.|..|:|                 |.|:|               |:||:.....:|..
Human    27 PREGPESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARK 91

  Fly   175 STPTTTLAPPTTAAAGALAGSPTSSSPSSSAASAAAAAAAAAAAAADLGAAAVASAAYGWNTAYS 239
            :.....|.||          :|..:||.:..|                 |||..|.|:......:
Human    92 ARTPCRLPPP----------APEPTSPGAEGA-----------------AAAPPSPAWSEPEPEA 129

  Fly   240 GLGPARSQFPYAQYASDYYGNAVGMSSSAAWFSHQERLYQPWSSQSYPGFNFDDIAFQTQLQRRS 304
            ||.|.|...|                                :....||.            |:.
Human   130 GLEPEREPGP--------------------------------AGSGEPGL------------RQR 150

  Fly   305 VRCTCPNCTNEMSGLPPIVGPDERGR---------KQHICHIPGCERLYGKASHLKTHLRWHTGE 360
            ||                     |||         ::|.||..|||::|||:||||.|||.||||
Human   151 VR---------------------RGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGE 194

  Fly   361 RPFLC--LTCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTH 413
            |||.|  ..|.|:|:|||||.||.||||..:.::||||.|:|.|||||:||.:.|
Human   195 RPFACSWQDCNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRH 249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
btdNP_511100.1 C2H2 Zn finger 338..357 CDD:275368 13/18 (72%)
zf-H2C2_2 349..374 CDD:290200 17/26 (65%)
C2H2 Zn finger 365..385 CDD:275368 12/21 (57%)
zf-H2C2_2 377..402 CDD:290200 14/24 (58%)
zf-C2H2 391..413 CDD:278523 13/21 (62%)
C2H2 Zn finger 393..413 CDD:275368 13/19 (68%)
KLF13NP_057079.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 23..57 5/29 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..166 29/186 (16%)
COG5048 <162..252 CDD:227381 52/88 (59%)
zf-C2H2 167..191 CDD:278523 16/23 (70%)
C2H2 Zn finger 169..191 CDD:275368 15/21 (71%)
zf-H2C2_2 183..210 CDD:290200 17/26 (65%)
C2H2 Zn finger 199..221 CDD:275368 12/21 (57%)
zf-H2C2_2 213..236 CDD:290200 13/22 (59%)
zf-C2H2 227..249 CDD:278523 13/21 (62%)
C2H2 Zn finger 229..249 CDD:275368 13/19 (68%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..288 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.