DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btd and znf281b

DIOPT Version :9

Sequence 1:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001012505.2	Gene:	znf281b / 503523	ZFINID:	ZDB-GENE-050220-1	Length:	826	Species:	Danio rerio

Alignment Length:	336	Identity:	76/336 - (22%)
Similarity:	124/336 - (36%)	Gaps:	59/336 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   324 GPDERGRKQHICHIPGCERLYGKASHLKTHLRWHTGERPFLCLTCGKRFSRSDELQRHGRTHTNY 388
            ||.....|.|||.  .|...:..:.||:.|:..|||||||.|..|...|.:...||||.:.|:..
Zfish   172 GPLSPSSKPHICE--HCSAAFRSSYHLRRHVLIHTGERPFRCSQCNMSFIQKYLLQRHEKIHSGE 234

  Fly   389 RPYACPICSKKFSRSDHLSKHKKTHFKDKKSKKVLAAEAKEQAAAAIKLEKKEKKSGKPLTPPVE 453
            :|::|..|:.:|.:..|:.:||:||..:|..|   .....:..:...:|.|.::..|:.:.
Zfish   235 KPFSCDQCNMRFIQKYHMERHKRTHSGEKPYK---CDTCLQYFSRTDRLLKHKRTCGEAIK---- 292

  Fly   454 FKQEQPDTTPL----VNYAPYANLYQHSTSAGSSVNPPPPPPPLFQQQMTTTTSSAAASFVEQPW 514
             |...|....|    :....|. |.|.:||.          ||..:.:     |.......|:..
Zfish   293 -KGLDPGMLDLGDEDMGQGSYL-LAQGNTSG----------PPRKKGK-----SKIGNDGGERRR 340

  Fly   515 SSSSSRAIQPATTSASSSSSSSASSPAAAVVSAI------GSASSPA-----------ASATALA 562
            ...::..::.|....:....|.:.:.:.|:..|.      |..|.|.           .|.:...
Zfish   341 KKGAAAGVRMARDDYNLDIPSGSGTASGALAEASMDNQHGGRTSKPVFKKGSRKGMDKCSVSVEE 405

  Fly   563 QHHYAALAMQSESQLAAEYGLTMSGL-----ASGASQDSSSSCH-------MKSEYAASYPADFG 615
            ..|...|..|..|.:......:|.||     :.|..|..:||.:       .|..|..:..::..
Zfish   406 ASHEQKLLTQKSSSMDMSGAGSMDGLGLLQNSGGTKQGGNSSNYDDAMQFLKKRRYLHAANSNAT 470

  Fly   616 AGTASYGYPHP 626
            |..:|...|.|
Zfish   471 ADFSSVHLPQP 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	4/18 (22%)
		zf-H2C2_2	349..374	CDD:290200	13/24 (54%)
		C2H2 Zn finger	365..385	CDD:275368	7/19 (37%)
		zf-H2C2_2	377..402	CDD:290200	9/24 (38%)
		zf-C2H2	391..413	CDD:278523	6/21 (29%)
		C2H2 Zn finger	393..413	CDD:275368	6/19 (32%)
znf281b	NP_001012505.2	zf-C2H2	181..203	CDD:278523	7/23 (30%)
		C2H2 Zn finger	183..203	CDD:275368	5/21 (24%)
		zf-H2C2_2	195..220	CDD:290200	13/24 (54%)
		C2H2 Zn finger	211..231	CDD:275368	7/19 (37%)
		zf-H2C2_2	224..248	CDD:290200	9/23 (39%)
		COG5048	235..>286	CDD:227381	13/53 (25%)
		C2H2 Zn finger	239..259	CDD:275368	6/19 (32%)
		zf-H2C2_2	251..276	CDD:290200	7/27 (26%)
		C2H2 Zn finger	267..286	CDD:275368	2/18 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010