DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btd and sp7

DIOPT Version :9

Sequence 1:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_998028.1	Gene:	sp7 / 405789	ZFINID:	ZDB-GENE-040629-2	Length:	440	Species:	Danio rerio

Alignment Length:	410	Identity:	133/410 - (32%)
Similarity:	185/410 - (45%)	Gaps:	88/410 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 SAAALLSAPPSLSGSSSGSSSGSSPLYGKPPMKLELPYPQASSTGTASPNSSIQSAPSSASVSPS 158
            |..|:|:|..:..||:|.....::|  |||..  .:|..:|.|.     .|.:|||.:..  :.|
Zfish    15 SPLAMLTATCNKFGSTSPVRDSATP--GKPGS--TIPIKKAYSM-----TSELQSAKNGR--NES 68

  Fly   159 IFPSPAQSFASISASPSTPTTTLAPPTTAAAGA-------LAGSPTSSSPSSSAASAAAAAAAAA 216
            :..|...||:| |....|||.:..|..|.|.|:       ...|..|..||...:.|.|....:.
Zfish    69 VADSYTGSFSS-SGGLLTPTGSPPPAPTGAYGSEYNPFSTFQTSSVSQDPSLLGSKATADCLTSV 132

  Fly   217 AAAADLG--------------AAAVASAAYGW---NTAYSGLGPARSQ-----------FPYA-- 251
            ....|:.              .|:.|:|...|   :|..:.|.|.::|           .|.|
Zfish   133 NTYLDMTHPYGSWYKGIHPGITASPANATSSWWDVHTNANWLSPGQAQPDSLQAPLQPVAPQASL 197

  Fly   252 -----QYASDY-------YGNAVGMSSSAAWFSHQER-----LYQPWSSQSYPGFNFDDIAFQTQ 299
                 .|..|:       | .:||:|||:......:.     :|:|   :..|.....|.:...:
Zfish   198 NPQMPSYTPDFTPLNPAPY-PSVGLSSSSHLLQSSQHMLPQDMYKP---KPVPTSGILDNSMGLK 258

  Fly   300 LQRRS----------VRCTCPNCTNEMSGLPPIVGPDERGRKQHICHIPGCERLYGKASHLKTHL 354
            ..|.|          ..|.|||| .|:..|..... ..|.:..|.||||||.::||||||||.||
Zfish   259 SARGSGYAAGSTTGRSSCDCPNC-QELERLGASAA-SLRKKPVHSCHIPGCGKVYGKASHLKAHL 321

  Fly   355 RWHTGERPFLC--LTCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTH---- 413
            |||||||||:|  |.|||||:|||||:||.||||..:.:.|.:|:|:|:||||||||:|||
Zfish   322 RWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCNKRFTRSDHLSKHQKTHSEAS 386

  Fly   414 FKDKKSKKVLAAEAKEQAAA 433
            .:.|:..:..|.|:.....|
Zfish   387 LQGKEEPETRAEESSADKVA 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	14/18 (78%)
		zf-H2C2_2	349..374	CDD:290200	21/26 (81%)
		C2H2 Zn finger	365..385	CDD:275368	15/21 (71%)
		zf-H2C2_2	377..402	CDD:290200	12/24 (50%)
		zf-C2H2	391..413	CDD:278523	13/21 (62%)
		C2H2 Zn finger	393..413	CDD:275368	13/19 (68%)
sp7	NP_998028.1	zf-C2H2	300..324	CDD:278523	18/23 (78%)
		zf-C2H2_8	302..386	CDD:292531	58/83 (70%)
		C2H2 Zn finger	305..324	CDD:275368	14/18 (78%)
		zf-H2C2_2	316..343	CDD:290200	21/26 (81%)
		C2H2 Zn finger	332..354	CDD:275368	15/21 (71%)
		zf-H2C2_2	346..371	CDD:290200	12/24 (50%)
		C2H2 Zn finger	362..382	CDD:275368	13/19 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910