DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btd and sp5

DIOPT Version :9

Sequence 1:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_989092.1	Gene:	sp5 / 394696	XenbaseID:	XB-GENE-1217606	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	393	Identity:	131/393 - (33%)
Similarity:	169/393 - (43%)	Gaps:	94/393 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 QQQQQQQQPQQQQHDFLSAAALLSAPPSLSGSSSGSSSGSSPLYGKPPMKLELPYPQASSTGTAS 141
            |.:.....|...:|   |..|||:|..|..|..           |..|... :.:|...:.|:.|
Frog    17 QDRTPSASPDVGKH---SPLALLAATCSRIGQP-----------GTGPADF-IQFPYDPTIGSPS 66

  Fly   142 ----PNSSIQSAPSSASVSP----SIFPSPAQSFASISASPSTPTTTLAPPTTAAAGALAGSPTS 198
                |.::..||.||..:.|    .:..|..|..:.|.:|..|....|.||...:. ....||..
Frog    67 RIFHPWTNEISAHSSGGIQPHNGIGLSTSKTQLASHIQSSFVTHELPLTPPADPSY-PYDYSPMK 130

  Fly   199 SSPSSSAASAAAAAAAAAAAAADLGAAAVASAAYGWNTAYSGL----------GPARSQFPYAQY 253
            ..|...||......:....|......|.:.||.:|:..::|.|          .||...
Frog   131 MLPPPMAAFQTGCQSPYVPAVPYAPPAPITSALHGFVPSHSNLIHQQPRQLSPNPAEDM------ 189

  Fly   254 ASDYYGNAVGMSSSAAWFSHQERLYQPWSSQS---YPGFNF-----------DDIAFQTQL---- 300
                           .|:|.|:.  .|.:..|   :|...|           |...:|||:
Frog   190 ---------------PWWSIQQA--TPVAHASTIPHPHHRFPIQRSLVLGHSDFAQYQTQIAALL 237

  Fly   301 --------QRRSVRCTCPNCTNEMSGLPPIVGPDERG-RKQHICHIPGCERLYGKASHLKTHLRW 356
                    .||..||.||||....       ||||.| :||||||||||.::|||.||||.||||
Frog   238 QTKSPLATARRCRRCRCPNCQTSS-------GPDEAGKKKQHICHIPGCGKVYGKTSHLKAHLRW 295

  Fly   357 HTGERPFLC--LTCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTHFKDKKS 419
            |:|||||:|  |.|||.|:||||||||.||||..:.:.||.|.|:|.|||||:||.||| ::||.
Frog   296 HSGERPFICNWLFCGKSFTRSDELQRHLRTHTGEKRFVCPECGKRFMRSDHLAKHVKTH-QNKKI 359

  Fly   420 KKV 422
            |.|
Frog   360 KSV 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	13/18 (72%)
		zf-H2C2_2	349..374	CDD:290200	19/26 (73%)
		C2H2 Zn finger	365..385	CDD:275368	15/21 (71%)
		zf-H2C2_2	377..402	CDD:290200	14/24 (58%)
		zf-C2H2	391..413	CDD:278523	13/21 (62%)
		C2H2 Zn finger	393..413	CDD:275368	13/19 (68%)
sp5	NP_989092.1	C2H2 Zn finger	277..296	CDD:275368	13/18 (72%)
		zf-C2H2	302..326	CDD:333835	16/23 (70%)
		C2H2 Zn finger	304..326	CDD:275368	15/21 (71%)
		zf-H2C2_2	318..341	CDD:372612	13/22 (59%)
		zf-C2H2	332..354	CDD:333835	13/21 (62%)
		C2H2 Zn finger	334..354	CDD:275368	13/19 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910