DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btd and ZNF367

DIOPT Version :9

Sequence 1:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_710162.1	Gene:	ZNF367 / 195828	HGNCID:	18320	Length:	350	Species:	Homo sapiens

Alignment Length:	359	Identity:	96/359 - (26%)
Similarity:	136/359 - (37%)	Gaps:	103/359 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 APSSASVSPSIFPSPAQSFASISAS---PSTPTTTLAPPTTAAAGALAGSP--TSSSP------- 201
            ||.:.:..|   |.|...|...|..   .|...||...||....|.....|  ..:||
Human     7 APMAENPPP---PPPPVIFCHDSPKRVLVSVIRTTPIKPTCGGGGEPEPPPPLIPTSPGFSDFMV 68

  Fly   202 --------------SSSAASAAAAAAAAAAAAADLGAAAVASAAYGWNTAYSGLGPARSQFPYAQ 252
                          |..||.|||:||..|||||:                :|||....:..|
Human    69 YPWRWGENAHNVTLSPGAAGAAASAALPAAAAAE----------------HSGLRGRGAPPP--- 114

  Fly   253 YASDYYGNAVGMSSSAAWFSHQERLYQPWSSQSYPGFNFDDIAFQTQLQRRSVRC-TCPNCTNEM 316
                    |...|::|:....:|....|.|.....|           ::|...|. |..:..||
Human   115 --------AASASAAASGGEDEEEASSPDSGHLKDG-----------IRRGRPRADTVRDLINE- 159

  Fly   317 SGLPPIVGPDERGRKQHICHIPGCERLYGKASHLKTHLRWHTGERPFLC--LTCGKRFSRSDELQ 379
                     .|....:..|:|  |.|::.:...|:.|.|.||||||:||  ..|||.|.:|.:|:
Human   160 ---------GEHSSSRIRCNI--CNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLK 213

  Fly   380 RHGRTHTNYRPYACPI--CSKKFSRSD-HLSKHKKTHFKDKKSKKVLAA-EAKEQAAAAIKL--- 437
            .|.|.||..:|:.|..  |..:|:.:: |..||.....|.::....|:. :|.:..|||..|
Human   214 THQRLHTGEKPFVCSENGCLSRFTHANRHCPKHPYARLKREEPTDTLSKHQAADNKAAAEWLARY 278

  Fly   438 -EKKEKKSGKPLTPPVEFK------QEQPDTTPL 464
             |.:|::     ||.::.|      |||.|  ||
Human   279 WEMREQR-----TPTLKGKLVQKADQEQQD--PL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	5/18 (28%)
		zf-H2C2_2	349..374	CDD:290200	15/26 (58%)
		C2H2 Zn finger	365..385	CDD:275368	9/21 (43%)
		zf-H2C2_2	377..402	CDD:290200	9/26 (35%)
		zf-C2H2	391..413	CDD:278523	6/24 (25%)
		C2H2 Zn finger	393..413	CDD:275368	6/22 (27%)
ZNF367	NP_710162.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	104..151		13/68 (19%)
		COG5048	167..>240	CDD:227381	29/74 (39%)
		zf-C2H2	168..189	CDD:278523	7/22 (32%)
		C2H2 Zn finger	169..189	CDD:275368	7/21 (33%)
		zf-H2C2_2	181..208	CDD:290200	15/26 (58%)
		C2H2 Zn finger	197..219	CDD:275368	9/21 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..327		7/18 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23235
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100