DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment btd and sptf-3

DIOPT Version :9

Sequence 1:NP_511100.1 Gene:btd / 31912 FlyBaseID:FBgn0000233 Length:644 Species:Drosophila melanogaster
Sequence 2:NP_493353.3 Gene:sptf-3 / 189783 WormBaseID:WBGene00012735 Length:412 Species:Caenorhabditis elegans


Alignment Length:442 Identity:129/442 - (29%)
Similarity:169/442 - (38%) Gaps:168/442 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 QQHQAQQQQHAQHQQHAQQQQHHLH--MQQAQHHLHLSHQQAQQQHMQHLT-------------- 62
            ||.|.....:.|.||..||||..:|  .|..||.:...:|..||||:...|              
 Worm    81 QQQQQPSSSNQQSQQQVQQQQQQVHQVQQVQQHQMQQQNQTVQQQHLMMETIDQVGSGIIGNSNG 145

  Fly    63 --QQQQQQQQQQQQQ--------------QQQQQQQQQPQQQQHDFLSAAALLSAPPSLSGSSSG 111
              ||||||||||||:              |:.|||||||||||..                    
 Worm   146 NNQQQQQQQQQQQQRRDPIPIAPAGMVSGQRMQQQQQQPQQQQQH-------------------- 190

  Fly   112 SSSGSSPLYGKPPMKLELPYPQASSTGTASPNSSIQSAPSSASVSPSIFPSPAQSFASI--SASP 174
                                 ..::||.::.|..:.:||    |.|.:......:..::  ...|
 Worm   191 ---------------------NNNNTGASTSNGGVNAAP----VMPVMGGQQRITLGNLHFQQDP 230

  Fly   175 STPTTTLAPPTTAAAGALAGSPTSSSPSSSAASAAAAAAAAAAAAADLGAAAVASAAYGWNTAYS 239
            :.|...:.              |:..|..:..||                               
 Worm   231 NDPQKWII--------------TNEGPPVAGPSA------------------------------- 250

  Fly   240 GLGPAR--SQFPYAQYASDYYGNAVGMSSSAAWFSHQERLYQPWSSQSYPGFNFDDIAFQ--TQL 300
               |||  :|..:.|.....  |..||.:.                    |.::.||..|  .:.
 Worm   251 ---PARKPNQIQHRQMIPQM--NEDGMMNM--------------------GNDYGDINGQGLGEA 290

  Fly   301 QRRSVRCTCPNC--TNEMSGLPPIVGPDERGRKQHICHIPGCERLYGKASHLKTHLRWHTGERPF 363
            .:|.. ||||||  .|...|       |.:.| .||||:  |.:.|||.|||:.|||.|.|.:||
 Worm   291 PKRCA-CTCPNCLQQNNRQG-------DGKSR-IHICHL--CNKTYGKTSHLRAHLRGHAGNKPF 344

  Fly   364 LC--LTCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTH 413
            .|  ..|.|:|:||||||||.||||..:.:||..|.|||.|||||:||::||
 Worm   345 ACDWQHCNKKFTRSDELQRHRRTHTGEKRFACNHCGKKFMRSDHLTKHERTH 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
btdNP_511100.1 C2H2 Zn finger 338..357 CDD:275368 10/18 (56%)
zf-H2C2_2 349..374 CDD:290200 13/26 (50%)
C2H2 Zn finger 365..385 CDD:275368 13/21 (62%)
zf-H2C2_2 377..402 CDD:290200 15/24 (63%)
zf-C2H2 391..413 CDD:278523 13/21 (62%)
C2H2 Zn finger 393..413 CDD:275368 12/19 (63%)
sptf-3NP_493353.3 COG5048 <311..406 CDD:227381 50/89 (56%)
C2H2 Zn finger 318..338 CDD:275368 12/21 (57%)
zf-C2H2 344..368 CDD:278523 14/23 (61%)
C2H2 Zn finger 346..368 CDD:275368 13/21 (62%)
zf-H2C2_2 360..383 CDD:290200 13/22 (59%)
zf-C2H2 374..396 CDD:278523 13/21 (62%)
C2H2 Zn finger 376..396 CDD:275368 12/19 (63%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 111 1.000 Domainoid score I3928
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 178 1.000 Inparanoid score I2684
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm14801
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
54.920

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