Protein Alignment btd and Klf3

DIOPT Version :10

• Sequence 1: NP_511100.1
• Gene: btd / 31912
• FlyBaseID: FBgn0000233
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_032479.1
• Gene: Klf3 / 16599
• MGIID: 1342773
• Length: 344
• Species: Mus musculus
• Alignment Length: 324
• Identity: 92/324 - (28%)
• Similarity: 129/324 - (39%)
• Gaps: 77/324 - (23%)

  Fly   115 GSSPLYGKPPMKLELPYPQASSTGTASPNSSIQSAPSSASVSPSIFPSP-AQSFASISASPSTPT 178
            ||.|..|..|..|:.|..:.:|.|.:.|:||    |.....||   ||| .|.|       ..|.
Mouse    70 GSPPAAGGSPSSLKFPSHRRASPGLSMPSSS----PPIKKYSP---PSPGVQPF-------GVPL 120

  Fly   179 TTLAPPTTAAAGALAG----------SPTSSSP-----SSSAASAAAAAAAAAAAAADLGAAAVA 228
            :  .||..|||.:..|          .|....|     :|........:.:.....::.|.....
Mouse   121 S--MPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMDNSNSGMPVPV 183

  Fly   229 SAAYGWNTAYS------GLGPARSQFPYAQYASDYYGNAVGMSSSAAWFSHQERLYQPWSSQSYP 287
            ..:|.......      |:.|.|:.: |.:..|....|.|....:....:|...:.||
Mouse   184 IESYEKPLLQKKIKIEPGIEPQRTDY-YPEEMSPPLMNPVSPPQALLQENHPSVIVQP------- 240

  Fly   288 GFNFDDIAFQTQLQRRSVRCTCPNCTNEMSGLPPIVGPD-ERGRKQHICHIPGCERLYGKASHLK 351
                         .:|.:               |:..|| :|.|:.|.|...||.::|.|:||||
Mouse   241 -------------GKRPL---------------PVESPDTQRKRRIHRCDYDGCNKVYTKSSHLK 277

  Fly   352 THLRWHTGERPFLCL--TCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTH 413
            .|.|.||||:|:.|.  .|..:|:|||||.||.|.||..:|:.||.|.:.|||||||:.|:|.|
Mouse   278 AHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRH 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	10/18 (56%)
		zf-H2C2_2	349..374	CDD:463886	13/26 (50%)
		C2H2 Zn finger	365..385	CDD:275368	11/21 (52%)
		zf-H2C2_2	377..402	CDD:463886	12/24 (50%)
		zf-C2H2	391..413	CDD:395048	12/21 (57%)
		C2H2 Zn finger	393..413	CDD:275368	12/19 (63%)
Klf3	NP_032479.1	Repressor domain	1..74		2/3 (67%)
		KLF3_N	49..259	CDD:410554	48/240 (20%)
		9aaTAD, inactive. /evidence=ECO:0000250|UniProtKB:P57682	60..68
		CTBP-binding motif	61..65
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..111		16/47 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	235..254		6/53 (11%)
		zf-C2H2	259..283	CDD:395048	12/23 (52%)
		C2H2 Zn finger	261..283	CDD:275368	11/21 (52%)
		C2H2 Zn finger	291..313	CDD:275368	11/21 (52%)
		zf-H2C2_2	305..330	CDD:463886	12/24 (50%)
		C2H2 Zn finger	321..341	CDD:275368	12/19 (63%)