DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btd and Egr3

DIOPT Version :9

Sequence 1:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_061251.1	Gene:	Egr3 / 13655	MGIID:	1306780	Length:	387	Species:	Mus musculus

Alignment Length:	385	Identity:	101/385 - (26%)
Similarity:	139/385 - (36%)	Gaps:	108/385 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 ELPYPQASSTGTASPNSSIQSAPSSASVS---PSIFPSPAQSFASISASPSTPTTTLAPPTTAAA 189
            |.|.|:.|.      :||.|.||.:.:|:   ...|.||:........|..:......||   |:
Mouse    62 EKPNPELSY------SSSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPP---AS 117

  Fly   190 GALAGSPTSSS---PSSSAASAAAAAAAAAAAAADLGAAAVA--------SAAYGWNTAYSGLGP 243
            |||:...:::|   |......|...|....:...||.:..|:        ..||. ...|....|
Mouse   118 GALSTQTSTASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYS-PQDYQSAKP 181

  Fly   244 A--RSQFP-YAQYASDYYGNAVGMSSSAAWFSHQE--RLYQP-----------WSSQSYPGFNFD 292
            |  .:.|| ...|...::.|.:|.......|...:  |:..|           ...|.:|||.
Mouse   182 ALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFG-- 244

  Fly   293 DIAFQTQLQRRSVRCTCPNCTNEMSGLPPIVGPDERGRK-------------QHICHIPGCERLY 344
                           :.|.        ||:.....|.||             .|.|...||:|.:
Mouse   245 ---------------SLPQ--------PPLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRF 286

  Fly   345 GKASHLKTHLRWHTGERPFLCLTCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLSKH 409
            .::..|..|||.|||.:||.|..|.:.|||||.|..|.||||..:|:||..|.:||:|||...:|
Mouse   287 SRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRH 351

  Fly   410 KKTHFKDKKSKKVLAAEAKEQAAAAIKLEKKEKKSGKPLTPPVEFKQEQPDTTPLVNYAP 469
            .|.|.|.|                    |||.:|.|.|          ...:.|.|:.||
Mouse   352 AKIHLKQK--------------------EKKSEKGGAP----------SASSAPTVSLAP 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	7/18 (39%)
		zf-H2C2_2	349..374	CDD:290200	12/24 (50%)
		C2H2 Zn finger	365..385	CDD:275368	10/19 (53%)
		zf-H2C2_2	377..402	CDD:290200	12/24 (50%)
		zf-C2H2	391..413	CDD:278523	10/21 (48%)
		C2H2 Zn finger	393..413	CDD:275368	9/19 (47%)
Egr3	NP_061251.1	DUF3446	87..147	CDD:314753	14/62 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	241..283		12/66 (18%)
		COG5048	269..>333	CDD:227381	27/63 (43%)
		C2H2 Zn finger	277..299	CDD:275368	8/21 (38%)
		COG5048	303..>375	CDD:227381	35/101 (35%)
		C2H2 Zn finger	307..327	CDD:275368	10/19 (53%)
		C2H2 Zn finger	335..355	CDD:275368	9/19 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..387		15/64 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I4686
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960