DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TAAR6 and LOC100488258

DIOPT Version :9

Sequence 1:	NP_778237.1	Gene:	TAAR6 / 319100	HGNCID:	20978	Length:	345	Species:	Homo sapiens
Sequence 2:	XP_012818683.1	Gene:	LOC100488258 / 100488258	-ID:	-	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	334	Identity:	147/334 - (44%)
Similarity:	215/334 - (64%)	Gaps:	5/334 - (1%)

- Green bases have known domain annotations that are detailed below.

Human    11 VQLCYANVNGSCVKIPFSPGSRVILYIVFGFGA-VLAVFGNLLVMISILHFKQLHSPTNFLVASL 74
            :.||:..||.||::...:|.:..:::|.. ||| :|...|||||:|||.||:|||.|||||:.||
Frog     1 MDLCFDFVNNSCLRTNRAPANYSVMFIAM-FGAIILTTVGNLLVIISISHFRQLHYPTNFLILSL 64

Human    75 ACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLV 139
            |.||||:|:.|||:||||::.||||||..||..|:|.|:..|..|::||.|||:|||.||..||.
Frog    65 ATADFLIGLVVMPYSMVRSLTSCWYFGDLFCKVHSCLDMTLCTGSIYHLFFISVDRYYAVCHPLH 129

Human   140 YPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNW-VLTDF 203
            |....|.:|..:.:..:|.:..::|..:.::.|:.:|:::...:..|||.|...:|:.| .::..
Frog   130 YYKNLTTNVIELFLLTTWSVSCVFSFGLVFSNVHTEGIQDYITSYYCIGSCSLTLNKLWGTISSL 194

Human   204 LSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFM 268
            :.||||..:||.:|.:||.|||.|||.:.|..|.....|:| |..| |.||||||||.:.:..|:
Frog   195 ICFFIPGALMIGIYMHIFSVARNQAKLVHNHHSFQPDKSKS-KISV-RAERKAAKTLSIVMGVFL 257

Human   269 ISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKN 333
            ..|||:.|.::||.::.|..|..:|.:..|..|:|||:||:|||||||||:||...|::|.:||.
Frog   258 FCWLPFFILTVIDPYINFSVPEDLYNVFLWLGYFNSALNPIIYALFYPWFQKAFACIISGNILKA 322

Human   334 SSATMNLFS 342
            .|:...|.:
Frog   323 GSSFSQLLT 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TAAR6	NP_778237.1	7tm_4	43..>271	CDD:304433	104/229 (45%)
TAAR6	NP_778237.1	7tm_1	49..311	CDD:278431	118/262 (45%)
LOC100488258	XP_012818683.1	7tmA_TAAR2_3_4	23..311	CDD:320437	133/290 (46%)
		TM helix 1	24..50	CDD:320437	13/26 (50%)
		TM helix 2	57..83	CDD:320437	18/25 (72%)
		TM helix 3	95..125	CDD:320437	15/29 (52%)
		TM helix 4	137..160	CDD:320437	3/22 (14%)
		TM helix 5	185..214	CDD:320437	11/28 (39%)
		TM helix 6	240..270	CDD:320437	14/29 (48%)
		TM helix 7	279..304	CDD:320437	12/24 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24249
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010