Protein Alignment TAAR6 and chrm2

DIOPT Version :9

• Sequence 1: NP_778237.1
• Gene: TAAR6 / 319100
• HGNCID: 20978
• Length: 345
• Species: Homo sapiens
• Sequence 2: XP_002942846.2
• Gene: chrm2 / 100485603
• XenbaseID: XB-GENE-6034896
• Length: 470
• Species: Xenopus tropicalis
• Alignment Length: 484
• Identity: 111/484 - (22%)
• Similarity: 176/484 - (36%)
• Gaps: 167/484 - (34%)

Human     4 NSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTN 68
            |:|.||.|    ::.|.:.:..|:.....|.:.||.|..:::.:.||:|||:||...:.|.:..|
 Frog     2 NNSSLVNV----SSTNETMMGSPYKTVEVVFIVIVAGSLSLVTIIGNILVMVSIKVNRHLQTVNN 62

Human    69 FLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIA 133
            :.:.||||||.::||..|....:.||...|..|...|......|.....:|:.:|..||.|||..
 Frog    63 YFLFSLACADLIIGVFSMNLYTLYTVIGYWPIGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 127

Human   134 VTDPLVYPTKFTVSVSGICISVSWILP-LMYSGAVFYTGVYDDG---------LEELSDALNCIG 188
            ||.||.||.:.|..::|:.|:.:|:|. ::::.|:.:......|         ::..|:|....|
 Frog   128 VTKPLTYPVRRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPEGECYIQFFSNAAVTFG 192

Human   189 GCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKK----------------------- 230
                        |...:|::|..||.:||..|...::.:.||
 Frog   193 ------------TAIAAFYLPVIIMTVLYWQISRASKSRIKKGKKEAAPNQDPISPSNVQGKIVK 245

Human   231 ----------------------------IEN---------------------------------- 233
                                        |||
 Frog   246 PNNNNVAANEDGLDHGKIQNGKVTSNSGIENCVQAEGEEKEISNDSTSVSVVNTKDEGAAKDVPQ 310

Human   234 -TGS----KTESS----------------------------------SESYKARVAR-------- 251
             :||    |||:|                                  .|..:..|||
 Frog   311 ASGSQANPKTENSKLTCIRIVTKSPKGDCSNATGTTVEIVPGANGRNGEDKQNIVARKIVKMTKQ 375

Human   252 ---------RERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMN 307
                     ||:|..:|:...::||:|:|.||::..||:.|.....|..::.|..|..|.||.:|
 Frog   376 PPKKKLPPSREKKVTRTILAILLAFIITWTPYNVMVLINTFCAVCVPNTVWTIGYWLCYINSTIN 440

Human   308 PLIYALFYPWFRKAIKVIVTGQVLKNSSA 336
            |..|||....|:|..|.::..|.....||
 Frog   441 PACYALCNTTFKKTFKHLLMCQYKNIGSA 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAAR6	NP_778237.1	7tm_4	43..>271	CDD:304433	77/378 (20%)
		7tm_1	49..311	CDD:278431	91/412 (22%)
chrm2	XP_002942846.2	7tmA_mAChR_M2	27..455	CDD:320424	100/439 (23%)
		TM helix 1	29..53	CDD:320424	10/23 (43%)
		TM helix 2	62..84	CDD:320424	10/21 (48%)
		TM helix 3	100..122	CDD:320424	4/21 (19%)
		TM helix 4	145..161	CDD:320424	3/15 (20%)
		TM helix 5	187..210	CDD:320424	8/34 (24%)
		TM helix 6	390..412	CDD:320424	7/21 (33%)
		TM helix 7	423..448	CDD:320424	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910