DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3106 and CG10183

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_651160.3	Gene:	CG10183 / 42782	FlyBaseID:	FBgn0039093	Length:	685	Species:	Drosophila melanogaster

Alignment Length:	710	Identity:	237/710 - (33%)
Similarity:	358/710 - (50%)	Gaps:	56/710 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LLTG----HSTPLASSFAHQFFTLASQSAELANRTNTQVIQTYEDRNYDDELCDRDINLIRDSIN 88
            ||.|    |::.|..........|:.....|....|.::|.|......|.: |..|:..:...:.
  Fly     9 LLCGLGHIHASHLKEELHLVHHRLSRFKESLFQDINHEIIDTRPSSTSDTQ-CLVDMKELFAGLK 72

  Fly    89 NLEEWALEFPDTWGRLPMGLFWGHTISMGQYEECV----AASSTHTTEIRGQYCLASLNITTFYQ 149
            ....|||:..|:||..|.||.:|....:|.::||:    ..||:.|  |:|:||..::.:    :
  Fly    73 TGSYWALKMLDSWGSFPSGLLYGTFYDLGNFDECLNINQEISSSQT--IKGKYCFMAVPL----R 131

  Fly   150 SVKKRGEEFSRISYKQTDPEVFELGICVPKTCSAAKTEKLLKYAITHFYGQ-------DVMESNY 207
            .|...|.|       ..:....::..|.|.:|||.:.|.        |.||       ..|..|.
  Fly   132 DVLDTGIE-------SLEGMQIKIATCFPASCSATQIET--------FAGQLYQNKVNSSMSFNI 181

  Fly   208 TMVTEARCKYDAPIELRGIDIFAIIFFSLIIFFMVASSVYDY-IQTRKGAPKKPLLIAFSVLTNA 271
            : :.|..|:...|:...|:.||.::..|::...:|:|::||| :.|.:..|  .|:...|...|:
  Fly   182 S-IDEDGCQTSDPVPWDGLTIFTVVILSVLTLIVVSSTLYDYFLCTTQQTP--ALIKIISARANS 243

  Fly   272 PKIFTVKKVN-NPNVIHCLNGLRCFSMMWVVFGHGYMTFYDLPHINKNKFYTWVQTPYSMLVQNG 335
            ..:|.::..| |.|||.||:|:||.|::||||.|.:|.....|:||......|::.|.|....:|
  Fly   244 RALFRLEVGNSNSNVIDCLHGIRCMSLIWVVFLHEHMYSLISPNINFTYALAWLEKPTSSFFIHG 308

  Fly   336 SLCVDTFFFMSGLLMCWGAFREMERTKGKLNIPMMYFHRYIRLTPVVAVVVLYIMSLYKYSGAGP 400
            ...||||.|:.|||:...|.|.||:|.||||||.||.||.||:.||:|:.:|..:.|......||
  Fly   309 YFSVDTFLFIGGLLVSLTALRTMEKTNGKLNIPRMYVHRIIRILPVLAMAILIYVKLMPVVSGGP 373

  Fly   401 MWFKLGTQDK-RCADTWWATLIYVQNYAFPYSICISQSWYLAVDTQLYFLSPLFLIPLWKWGKKA 464
            : ||.|...| .|.:.|:..|:::||||  ...|:.||||||||.|||.||||.|..|:||||||
  Fly   374 L-FKSGFHGKEECVNGWYWDLLFIQNYA--TKTCLDQSWYLAVDMQLYILSPLLLFGLYKWGKKA 435

  Fly   465 LVPIVIVLILCLGGTFATFMLNDFTLFRVQ---DDQVDLRQRLTYYPTHTRIPTWLIGVIFGYFL 526
            ...||.:::|..|..|||.|:|.:::....   ||:.:.:   .|..|||....||||.:|||||
  Fly   436 AWAIVGIVVLLSGCLFATQMVNHYSMSIKNGGGDDEANSK---LYLATHTHATPWLIGFLFGYFL 497

  Fly   527 FTRNRGRQIPMSKPLVLTGWFVAFGTMLACMWGPYWRILPDTPDSPLIEGAFFEPLSRTSWALSI 591
            . .||||:..:|..::.:|||::...:...::..|.......|....::.:.:..|:|..|.|::
  Fly   498 H-MNRGRKFQLSWLVLWSGWFISLAMIFTSIFATYPSAKWSAPPLSTLDESLYYTLTRVGWPLAM 561

  Fly   592 GWIVWACYNGHGGLVNDFLSWGFFTGFSRLCYCMYVIHRIVQLVNAARLQTDTHFSNYDAILRWW 656
            .|:|:.|..|:.||.|.|||...:...|||.|.:::.|..||.:|:..::|.|:||:|..:|.:|
  Fly   562 CWVVFVCIQGYCGLANSFLSTPLWQPLSRLSYSVFIWHMFVQEINSRNVRTSTYFSSYTVMLNFW 626

  Fly   657 HDFGITLTASIFATLAFEAPILGIEKAIFGKPAPKKPSPGELAKAAPVAATSASAEPEPE 716
            .||||:|..|....|..||||.|:..........|.|   |:.:.......:.....|||
  Fly   627 SDFGISLIMSYVLYLIIEAPIGGLHSLWSRTGCTKSP---EVVRPVLTFVVNQRNGDEPE 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781	36/136 (26%)
		Acyl_transf_3	286..635	CDD:280013	142/352 (40%)
		OafA	289..702	CDD:224748	163/416 (39%)
CG10183	NP_651160.3	NRF	75..190	CDD:214781	36/136 (26%)
		OafA	245..647	CDD:224748	164/408 (40%)
		Acyl_transf_3	259..641	CDD:280013	156/388 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458075
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	12	11.800