DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3106 and oac-32

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_001300114.1	Gene:	oac-32 / 186125	WormBaseID:	WBGene00018708	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	755	Identity:	194/755 - (25%)
Similarity:	317/755 - (41%)	Gaps:	167/755 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LASQSAELANRTNT-----QVIQTYEDRNYDDELCD-RDINLIRDSINNLEEWALEFPDTWGRLP 105
            |.:.||:..|.|||     ::..|........:.|: :::.::||::     :|::..|.:|:.|
Worm    32 LDNLSAQCLNDTNTWINSLEIFGTLYAECIIMKKCNAKELKVLRDNL-----YAVQQLDAFGQFP 91

  Fly   106 -MGLFWGHTISMGQYEECVAASSTHTTEIRGQYCLASLNITTFYQSVKKRGEEFSRISYKQTDPE 169
             .||....|:..|.|:||...|.   .:....||...|   |..::|.......|:..|.|..
Worm    92 GAGLLELKTLYDGSYQECQRVSG---KKYDVNYCYLLL---TPGKNVSSCAPSNSKSLYSQLP-- 148

  Fly   170 VFELGICVPKTCSAAKTEKLLKYAITHFYGQDVME-----SNYTMV------TEARCKYDAPIEL 223
             ..:.:|:|.:|:             |   ||:::     |.|...      |:...|.|.|  .
Worm   149 -LRIAVCLPDSCN-------------H---QDMIDIFNELSPYPFTACSAYCTKNEVKKDTP--F 194

  Fly   224 RGIDIFAIIFFSLIIFFMVASSVYDYI-QTRKGAPKK-------PLLIAFSVLTNAPKIFTVKKV 280
            .|..||.|:   :::...:| |:.||: :|..|...:       .:|:.||:.|||..:.:||:
Worm   195 WGFSIFLIV---MVVIAAIA-SIVDYVRETVYGLSSQKENNTFFKILLTFSLWTNAELLLSVKE- 254

  Fly   281 NNPNVIHCLNGLRCFSMMWVVFGHGYM---------TFYDLPHINKNKFYTWVQTPYSMLVQNGS 336
            .....|..|:.:|..||.|||.||.::         ...|.|      .|.|     :.|:.|..
Worm   255 QKSGFIKSLDCIRLLSMCWVVTGHSFLYLILADTLEPVLDFP------TYFW-----NHLLLNAF 308

  Fly   337 LCVDTFFFMSGLLMCWGAFREMERTKGKLNIPM----MYFHRYIRLTPVV-------AVVVLYIM 390
            :.|||||.:||:::.: .|.:.:.||..:..||    .|.|||:||||.|       .|...||.
Worm   309 VSVDTFFVLSGIVVAY-LFFKTKLTKKTITSPMTWILFYVHRYLRLTPPVMLFIGFFTVYTPYIQ 372

  Fly   391 SLYKYSGAGPMWFKLGTQDKRCADTWWATLIYVQNY---AFPYSICISQSWYLAVDTQLYFLSPL 452
            ..:..|....|    ..|...|...||..|:|:.|:   ....|.|...:||||||||||.::|:
Worm   373 GAFSASELNQM----APQAAACKTLWWQNLLYINNFDDGNSQNSTCYGITWYLAVDTQLYLVAPI 433

  Fly   453 FLIPLWKWGKKALVPIVIVLILCLGGTFATFMLNDFTLFRVQDDQVDLRQR-----LTYYPTHTR 512
            .|:.|:   ........|::..|:|....|::|  |.::.|..|.:....:     :.|.....|
Worm   434 VLVALY---FSFAAGTAIIVAGCVGSIITTYIL--FGVYNVPADIIGNGDQTKFFNIAYSKPWIR 493

  Fly   513 IPTWLIGVIFGYFLFTRNRGRQIPMSKPLVLTGWFVAFGTMLACMW-------GPYWRILPDTPD 570
            .|.:|:|::.||.|.|.. .|:|.::..|.:.||..||.....|::       |.:|
Worm   494 CPPYLVGLLTGYLLATYG-SRKIRLNWALAIAGWITAFVIAGFCLFATYDYDKGAHW-------- 549

  Fly   571 SPLIEGAFFEPLSRTSWALSIGWIVWACYNGHGGLVNDFLSWGFFTGFSRLCYCMYVIHRIVQLV 635
            |......|:. ..|..|.:.:.|:|.|.:.|.||.::.|:|...:..|.||.||.|::|.:|..
Worm   550 STFTRATFYN-FHRLGWGVFVCWVVGANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWMVLY- 612

  Fly   636 NAARLQTDTHFSNYDAILRW---WHDFG-ITLTASI-------FATLAFEAPILGIEKAIF---- 685
                     ::.|...:|.:   |..|. |.:.|::       |.:..||.|||.:||.:.
Worm   613 ---------YYLNVGGVLHYSSAWQVFTYIAIPATLLSYVLAFFWSCLFEVPILKLEKMLIEKLI 668

  Fly   686 ---GKPAPKKPSPGELAKAAPVAATSASAEPEPEAKPESV 722
               |:.:.|....|:          :....|:.||:.|.|
Worm   669 GGGGRTSLKVEDLGK----------NIGKVPDEEAENEKV 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781	29/137 (21%)
		Acyl_transf_3	286..635	CDD:280013	111/383 (29%)
		OafA	289..702	CDD:224748	127/465 (27%)
oac-32	NP_001300114.1	NRF	77..185	CDD:214781	28/137 (20%)
oac-32	NP_001300114.1	OafA	254..659	CDD:224748	123/446 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.720