DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3106 and oac-14

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_509701.1	Gene:	oac-14 / 181226	WormBaseID:	WBGene00008602	Length:	710	Species:	Caenorhabditis elegans

Alignment Length:	710	Identity:	190/710 - (26%)
Similarity:	313/710 - (44%)	Gaps:	125/710 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 RDINLIRDSINNLEEWALEFPDTWGRLPM-GLFWGHTISMGQYEECVAASSTHTTEIRGQYCLAS 141
            :::.:::.::     :|::..|::|:||: |:....|:..|.|:||...|.   .:....||...
Worm    68 KELKILKANL-----YAIQELDSFGKLPVPGMLEVATLYDGSYQECKRVSG---VKYNTNYCYLM 124

  Fly   142 LNITTFYQSVKKRGEEF------SRISYKQTDPEVFELGICVPKTCSAAKT----EKLLKYAIT- 195
            |          |.|:..      |..:|....   ..|.:|:|.:|:..:.    .:|..|..|
Worm   125 L----------KPGKNASCSASGSSSAYSMLP---MRLAVCLPDSCNQHEIIDIFNQLSPYPFTA 176

  Fly   196 -HFYGQDVMESNYTMVTEARCKYDAPIELRGIDIFAIIFFSLIIFFMVASSVYDYIQTRKGAPKK 259
             |.|           .:|...|.|.|  ..|..||.|:    ::...:|:|:.|||:......|.
Worm   177 CHAY-----------CSEYEVKKDTP--FWGFSIFLIV----MVVIALAASLTDYIRDTVYGIKS 224

  Fly   260 --------PLLIAFSVLTNAPKIFTVKKVNNPNVIHCLNGLRCFSMMWVVFGHGYM------TFY 310
                    .:|::||:.|||..:.:||: ..|..|..|:.:|.|||.|||.||.::      ||
Worm   225 IKERNVFLKILLSFSLWTNAELLLSVKE-QKPGFIKSLDCIRLFSMCWVVTGHSFIYLVLSDTF- 287

  Fly   311 DLPHINKNKFYTWVQTPYSMLVQNGSLCVDTFFFMSGLLMCWGAFREMERTKGKLNIP----MMY 371
             :|.|:..|.:      ::.|:.|..:.|||||.:|||::.:..|:...:.|..:| |    |.|
Worm   288 -MPVIDFPKHF------WNHLLLNAFVSVDTFFVLSGLVLTYMFFKTTPKKKMIVN-PVTWIMFY 344

  Fly   372 FHRYIRLTPVVAVVVLYIMSLYKYSGAGP----MWFKLGTQDKRCADTWWATLIYVQNYAFPYSI 432
            .|||:||||.:.:.:.: .::|.....||    ...:|..:...|..|||..|:|:.::|...|:
Worm   345 VHRYLRLTPPIMLFIGF-FTVYAPYIQGPFSASQMNQLVMEADECKTTWWQNLLYINDFASSNSM 408

  Fly   433 -CISQSWYLAVDTQLYFLSPLFLIPLWKWGKKALVPIVIVLILCLGGTFATFMLNDFTLFRVQDD 496
             |...:||||||||||.::|:.||.|:   ....|...:::..|:|....|::|  |:::.:..|
Worm   409 GCYGPTWYLAVDTQLYLVAPIVLIGLY---FSFAVGTGLIVAGCVGSIITTYIL--FSVYNLPAD 468

  Fly   497 QVDLRQ-----RLTYYPTHTRIPTWLIGVIFGYFLFTRNRGRQIPMSKPLVLTGWFVAFGTMLAC 556
            ......     .:.|.....|.|.:|:|::.||.|.... .|:|.::..|.|.||.:|......|
Worm   469 MFGNGSGTNFFTIAYEKPWVRCPPYLVGMLTGYLLAVYG-NRKIRLNWVLSLAGWIIAVVIAGFC 532

  Fly   557 MW-------GPYWRILPDTPDSPLIEGAFFEPLSRTSWALSIGWIVWACYNGHGGLVNDFLSWGF 614
            ::       |.:|        |....|.|:. ..|..|.:.|.|:|.|.:.|.||.::.|:|...
Worm   533 LFATYDYDKGSHW--------SVFTRGTFYN-FHRLGWGMFICWVVAANHMGWGGPIDKFMSHPI 588

  Fly   615 FTGFSRLCYCMYVIHRIVQLVNAARLQTDTHFSNYDAILR--WWHDFGITLTASIFA---TLAFE 674
            :..|.||.||.|::|.:|..   ..|....|.::|.:.|.  .:.....|..:.|||   :..||
Worm   589 WQPFGRLSYCAYIVHWVVLF---WFLNVGGHATHYYSALEVFTYTSIPATFLSYIFAFFWSCLFE 650

  Fly   675 APILGIEK----AIFGKPAP-KKPSPGELAKAAPVAATSASAEPEPEAKPESVVETKTEI 729
            .|.|.:||    ||.|...| .|..|.|..|..|:...........|...|...:..|::
Worm   651 IPTLKLEKMLIEAILGTGRPSNKVEPIETGKTTPILEKKLEGNGWIEEVKEEKFDENTKV 710

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781	29/138 (21%)
		Acyl_transf_3	286..635	CDD:280013	113/375 (30%)
		OafA	289..702	CDD:224748	134/449 (30%)
oac-14	NP_509701.1	NRF	76..183	CDD:214781	28/138 (20%)
oac-14	NP_509701.1	OafA	252..656	CDD:224748	126/432 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.720