DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3106 and oac-6

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_507118.1	Gene:	oac-6 / 180094	WormBaseID:	WBGene00007833	Length:	705	Species:	Caenorhabditis elegans

Alignment Length:	746	Identity:	191/746 - (25%)
Similarity:	313/746 - (41%)	Gaps:	165/746 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VVLLIATAVGAQDTSSNYL-------LTGHSTPLAS---SFAHQFFTLASQSAE--LANRTNTQV 62
            :|.|.|| |..::....:|       :||.|...|:   ::......:|..|||  :..:...:.
Worm    10 IVCLFAT-VFCENWKEVFLAKAADQKITGVSEQCANDTETWQKSLKMVAELSAECLIEQKCTKEE 73

  Fly    63 IQTYEDRNYDDELCDRDINLIRDSINNLEEWALEFPDTWGRLPM-GLFWGHTISMGQYEECVAAS 126
            ::|.||..|                      |:|..|.||::|: |||....:..|.|:||...|
Worm    74 LKTIEDNFY----------------------AVEQYDAWGKIPLTGLFQLPILFDGSYQECERIS 116

  Fly   127 STHTTEIRGQYCL--------ASLNI-----TTFYQSVKKRGEEFSRISYKQTDPEVFELGICVP 178
            .   .:....||.        |:.::     |||:                      |...:|:|
Worm   117 G---KKYATNYCYMVLMPGKNATCHMSDGLPTTFF----------------------FRGAVCMP 156

  Fly   179 KTCSAAKTEKLLKYAITHFYGQDVMESNYTMVTEARCKYDAPIELRGIDIFAIIFFSLIIFFMVA 243
            .:||        :..:...|.| |.:..:|........|  |::..........|.:::|...:.
Worm   157 YSCS--------EQDLPTVYNQ-VSDQPFTACAAFCSSY--PVKKTPAFWGFTSFMAVMIGIALL 210

  Fly   244 SSVYDYIQTRKGAPKK-----------PLLIAFSVLTNAPKIFTVKKVNNPNVIHCLNGLRCFSM 297
            ::|.||:   |.|.||           .:|:.||:.|||..:.:||: ..|..|.||:.:|..||
Worm   211 ATVIDYL---KDALKKEDEKREDSRILQILLTFSLWTNAELLLSVKE-QKPGFIKCLDCIRFLSM 271

  Fly   298 MWVVFGH--GYMTFYD-----LPHINKNKFYTWVQTPYSMLVQNGSLCVDTFFFMSGLLMCWGAF 355
            :|||.||  .|:|..|     ||...:    .|     :.||.|....|||||.:|||::.:..|
Worm   272 LWVVTGHTFSYLTTPDQIESILPFFGR----FW-----NHLVMNAFYSVDTFFLLSGLVVSYLFF 327

  Fly   356 R---EMERTKGKLNIPMMYFHRYIRLTPVVAVVVLYIMSLYKYSGAGPMWFKLGTQD---KRCAD 414
            :   ::.:.|..:...:.|.|||:||||.:...:.:.:...||.....:..:|..|:   ..|..
Worm   328 KTKLKVSQIKSPITWILFYVHRYLRLTPPLMFFLGFFVVYGKYFQGPGVASQLNQQNGEVDTCQT 392

  Fly   415 TWWATLIYVQNYAFPYSICISQSWYLAVDTQLYFLSPLFLIPLW---KWGKKALVPIVIVLILCL 476
            .||..|||:.|.....:.|...:|||..|||||.::|:|||.|:   ..|...|....|..::.:
Worm   393 YWWKNLIYINNLMSGDTQCYGITWYLGADTQLYLVAPIFLIGLYFSFAIGTALLTAATIGSVITV 457

  Fly   477 GGTFATFML-------NDFTLFRVQDDQVDLRQRLTYYPTHTRIPTWLIGVIFGYFLFTRNRGRQ 534
            ...|:|:.|       .|.|.|          ..:.|.....|.|.:.:|::.||.|.|..: |:
Worm   458 YILFSTYDLPADFFGNGDATHF----------YDMIYIKPWIRCPPYFVGILVGYLLATYGK-RK 511

  Fly   535 IPMSKPLVLTGWFVAFGTMLACMWGPY-------WRILPDTPDSPLIEGAFFEPLSRTSWALSIG 592
            :.::..|.:|||.|||.....|::..|       |.|         ...|.:...||.:|:.::.
Worm   512 LRLNWALAVTGWIVAFSLGALCIFSTYDYDNKVKWSI---------FSRATYYNFSRLAWSFALS 567

  Fly   593 WIVWACYNGHGGLVNDFLSWGFFTGFSRLCYCMYVIHRIVQLVNAARLQTDTHF-SNYDAILRWW 656
            |::.|.:.|.||.::.|:|...:..|.||.||.|::|.:|..:.........|| |::...:  :
Worm   568 WVIVANHMGWGGPIDAFMSHPMWQPFGRLSYCAYIVHYVVLYMYLMIGDASIHFYSSFQIFM--Y 630

  Fly   657 HDFGITLTASIFA---TLAFEAPILGIEKAI 684
            :....|:.:.|||   :..||.|.|.:||.:
Worm   631 YAVPTTVLSYIFAFFWSCLFEIPFLKLEKML 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781	29/139 (21%)
		Acyl_transf_3	286..635	CDD:280013	111/378 (29%)
		OafA	289..702	CDD:224748	122/430 (28%)
oac-6	NP_507118.1	NRF	80..185	CDD:214781	30/160 (19%)
oac-6	NP_507118.1	Acyl_transf_3	260..644	CDD:376607	117/414 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.720