DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3106 and oac-55

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_001317839.1	Gene:	oac-55 / 178792	WormBaseID:	WBGene00021479	Length:	742	Species:	Caenorhabditis elegans

Alignment Length:	664	Identity:	176/664 - (26%)
Similarity:	281/664 - (42%)	Gaps:	110/664 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 EEWALEFPDTWGRLPMGLFWGHTISMGQYEECVAA---SSTHTTEIRGQYCLASLNITTFYQS-- 150
            :::.:...|..|:|..|:..||.:|.|.:.||.:.   ||:....::|.|          |.|
Worm   111 KDYLIPMMDAAGKLGSGIVRGHILSTGAFSECKSIQMFSSSLNRTVQGDY----------YSSRI 165

  Fly   151 ---VKKRGEEFSRISYKQTDPEVFELGI--CVPKTCSAAKTEKLLKYAITHFYGQDVMESNYTMV 210
               :|.|...|:      :...:.::|:  |:|.:|   :.|.|..| .....|.....|....|
Worm   166 LFDMKMRPNSFN------SSCNLPQIGVDLCLPWSC---RNEDLTGY-FREALGPSKALSPVCSV 220

  Fly   211 TEARCKYDAPIELRGIDIFAIIFFSLIIFFMVASSVYDYIQ-------TRK--GAPKKPLLIAFS 266
            .....:  .|:...|..| .::..|||:...:.|...|..|       |||  |...| |..|||
Worm   221 RNVNQR--VPVISLGTWI-VLLILSLIVGLCILSGFSDIFQKFQLNDKTRKEEGFGWK-LFSAFS 281

  Fly   267 VLTNAPKIFTVKKVNNPNVIHCLNGLRCFSMMWVVFGH-GYMTFYDLPHINKNKFYTWVQTPYS- 329
            ...|..:||..|..:....:..||.:|..|..||:||| ..:||..:  .|....|.:.:..|:
Worm   282 FHRNLKEIFNTKNCHKEGQVTSLNCIRVISTFWVIFGHCSEITFMVI--TNPIDLYDFTKDTYTG 344

  Fly   330 MLVQNGSLCVDTFFFMSGLLMCWGAFREMERTKGKLNIP----MMYFHRYIRLTPVVAVVVLYIM 390
            .|:.|....||||||:|..|:.:..|:::|:....|..|    |.|.||..||:||..|.:|:..
Worm   345 TLISNAYFSVDTFFFISAFLLSFLWFKQLEKQWNALLSPGGWLMFYVHRIARLSPVYYVTILFFT 409

  Fly   391 SLYKYSGAG-PMWFKLGTQDKRCADTWWATLIYVQNYAFPYSICISQSWYLAVDTQLYFLSPLFL 454
            .::..|... |.:......|..|.:::|..|:|:||...|..||...|||||.|.|:|.:|||.|
Worm   410 FVFTRSMVDMPAFMTPAVVDDTCQNSYWVNLLYIQNIVGPKDICYFISWYLATDLQIYIMSPLIL 474

  Fly   455 IPLWKWGKKALVPIVIVLILCLGGT--------FATFMLNDFTLFRVQDDQVDLRQR----LTYY 507
            :.....|  |:|.::|.....|..|        |..|..:|:. :..:|...|..:|    ..|:
Worm   475 LSFGLGG--AVVGLLISTAAFLASTAFNAYQMIFWHFPPSDYN-YGPKDPLYDPSKRRYAAWNYH 536

  Fly   508 PTHTRIPTWLIGVIFGYFLFTRNRGRQIPM--SKPLV-LTGWFVAFGTML-----------ACMW 558
            ....|...:::|::.|||:      |:||.  ..|.| ...|.::.|:|:           ..:|
Worm   537 NPLIRCQIYIMGMVLGYFM------RRIPKININPWVDRIMWCLSLGSMIFVIVIMEDYTSGHLW 595

  Fly   559 GPYWRILPDTPDSPLIEGAFFEPLSRTSWALSIGWIVWACYNGHGGLVNDFLSWGFFTGFSRLCY 623
            .|             ::.|.:...||..|.|::.|||.:.|. ..||:|.|:|...:|..:||.:
Worm   596 SP-------------LQTALYSCFSRVVWGLALSWIVISTYY-RKGLINKFMSLPVWTPLARLSF 646

  Fly   624 CMYVIHRIVQLVNAARLQTDTHFSN--YDAILRWWHDFGITLTASIFATLAFEAPILGIEKAIFG 686
            |.|::|.:|......|..::.:||.  |..::........:...:||.:..||.|...:|..:.|
Worm   647 CAYLVHLMVAAYFFGRNHSELYFSTLPYFVLVIAIPVISCSFLVAIFWSTMFELPFAKVEALLLG 711

  Fly   687 -------KPAPKKP 693
                   ...||.|
Worm   712 GGSRSSAPDIPKTP 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781	29/135 (21%)
		Acyl_transf_3	286..635	CDD:280013	111/381 (29%)
		OafA	289..702	CDD:224748	125/447 (28%)
oac-55	NP_001317839.1	NRF	111..220	CDD:214781	28/128 (22%)
oac-55	NP_001317839.1	OafA	299..690	CDD:224748	115/415 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720