DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3106 and oac-39

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_001300160.1	Gene:	oac-39 / 178553	WormBaseID:	WBGene00006419	Length:	739	Species:	Caenorhabditis elegans

Alignment Length:	682	Identity:	170/682 - (24%)
Similarity:	289/682 - (42%)	Gaps:	137/682 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 DTWGRLPMGLFWGHTISMGQYEECVAASSTHTTE----IRGQYCLASLNITTFYQ---SVKKRGE 156
            |..|::..|:..||.:|.|.:.||.:. |.|:|.    |||.|          |:   .:|.|..
Worm   115 DAAGKIGSGIARGHILSAGAFTECKSV-SMHSTSLNRTIRGDY----------YRILFDIKMRPN 168

  Fly   157 EFSRISYKQTDPEVFELG--ICVPKTCSAAKTEKLLKYAITHFYGQDVMESNYTMVTEARCKYDA 219
            .|:      ...::.::|  ||:|.:|   :.|.|               ::|........|..:
Worm   169 SFN------DSCQLPQIGVDICLPWSC---RNEDL---------------TDYFREALGATKELS 209

  Fly   220 PI-ELRGID-----------IFAIIFFSLIIFFMVASSVYDYIQTRK---------GAPKK--PL 261
            |: .:|.::           :...:..|:|...:|:.:|..|.|.|:         |:...  .:
Worm   210 PVCSVRNVNGRTPGFTFGTYVVVTLILSIIATSIVSCTVDYYFQNRRSKIDYERMEGSSNVGWKI 274

  Fly   262 LIAFSVLTNAPKIFTVKKVNNPNVIHCLNGLRCFSMMWVVFGHGYMTFYDLPHINKNKFYTWVQT 326
            .:|||:..|..:||.:|:.|....:..||.:|..|.:||:.|| ......|...|......:.:|
Worm   275 FMAFSLYRNVKEIFKMKQCNKEGQVTSLNCIRTISTVWVILGH-CAAMLILICTNPVDLLDFTKT 338

  Fly   327 PYSMLVQNGSLCVDTFFFMSGLLMCWGAFREMERTKGKLNIP----MMYFHRYIRLTPVVAVVVL 387
            ....|:.|....||||||:|..|:.:..|:::::.:..|..|    |.|.||..||:|...:.:|
Worm   339 YMGALLVNAYFAVDTFFFISAFLLSFLWFKQLQKQRKALISPGGWMMFYVHRIARLSPAYYIAIL 403

  Fly   388 YIMSLY-KYSGAGPMWFKLGTQDKRCADTWWATLIYVQNYAFPYSICISQSWYLAVDTQLYFLSP 451
            ::..:| :.....|.:.....||..|...:|..|:|::|.....:||...|||||.|.|||.:||
Worm   404 FVTFVYIRMLRDMPAFMSPAIQDDTCQQNYWLNLLYIENIVDTKNICYVISWYLATDLQLYLMSP 468

  Fly   452 LFLIPLWKWGKKALVPIVIVLILCLGGTFATFMLNDFTLF-----------RVQDDQVDLRQR-- 503
            :.|:..      |:...|..|...:....|:...|.:.:|           ..:|.:.:..:|
Worm   469 ILLLSF------AIGGAVFGLFASVVALVASTAFNAYQIFFWYFPPTDYPLGPKDPRYNENERRY 527

  Fly   504 --LTYYPTHTRIPTWLIGVIFGYFLFTRNRGRQIPM--SKPLV-LTGWFVAFGTMLACMW----- 558
              ..||....|...:::|::.|||:      |::|.  ..|.| ...|.::.|:|:..:.
Worm   528 DVWNYYNPLIRCQIYIMGLVLGYFM------RKVPKININPWVDRIMWVLSLGSMVFVVLVIQDY 586

  Fly   559 --GPYWRILPDTPDSPLIEGAFFEPLSRTSWALSIGWIVWACYNGHGGLVNDFLSWGFFTGFSRL 621
              |..|     ||    ::.|.:...||..|..::.|||.:.|. ..||:.||:|..|:|..:||
Worm   587 SSGDGW-----TP----VQTALYSCFSRVLWGFAMSWIVISTYY-RKGLIRDFMSLSFWTPLARL 641

  Fly   622 CYCMYVIHRIVQLVNAARLQTDTHFSNYDAILRWWHDFGITLTA-----SIFATLAFEAPILGIE 681
            .:|.|::|.:|......|..::.:||   .:..::.|..|.:||     :||.:..||.|...||
Worm   642 SFCAYLVHWMVLGYFFGRNHSELYFS---TLSYFFLDTVIPVTALSFVIAIFWSSMFEIPFAKIE 703

  Fly   682 KAIFGKPAPKKPS---------PGELAKAAPV 704
            ..:.|:....|.:         |.|:.||..|
Worm   704 GLLLGRSGTPKANGNLPKVMIIPLEIPKAGEV 735

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781	28/126 (22%)
		Acyl_transf_3	286..635	CDD:280013	102/378 (27%)
		OafA	289..702	CDD:224748	121/456 (27%)
oac-39	NP_001300160.1	NRF	109..218	CDD:214781	31/137 (23%)
oac-39	NP_001300160.1	OafA	297..685	CDD:224748	109/413 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.720