DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3106 and rhy-1

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_495954.1	Gene:	rhy-1 / 174455	WormBaseID:	WBGene00012324	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	505	Identity:	112/505 - (22%)
Similarity:	188/505 - (37%)	Gaps:	144/505 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 SVLTNAPKIFTVKKVNNP----------------NVIHC--------------------LNGLRC 294
            |.||||....||:..::|                :|..|                    |:..|.
Worm    36 SCLTNAFIPDTVRMASSPLLAWMTLVVIGTLAPVSVFSCLSLKRSVKELLTERSSKLDVLDIFRF 100

  Fly   295 FSMMWVVFGH----GYMTFYD-LPHINKNKFYTWVQTPYSMLVQNGSLCVDTFFFMSGLLMCWGA 354
            .:::||:..|    |.:...| ||..:..|........:..|:.|.:|.|:.|..:||||.....
Worm   101 VAILWVMLNHTGSEGRIDILDRLPSADAFKSAMHDHPIFGALMGNSALGVEIFLVLSGLLAARSW 165

  Fly   355 FREMERTKGKLNIPMMYF--------HRYIRLTPVVAVVVLYIMSLYKYSGAGPMWFKL-----G 406
            .|:.:..         :|        .|.:||.|        .|.::.|..|||:...|     .
Worm   166 LRKADEP---------FFQHWKSFIARRLLRLAP--------SMFIFVYIAAGPIMNALLPRYSS 213

  Fly   407 TQDKRCADTWWATLIYV---QNY-AFPYSICISQSWYLAVDTQLYFLSPLFLIPLWKWGKKAL-- 465
            :....|.  :|..|.:|   .|: :.|  .|:...|||.:|.|||.::|:||..|.|:.|:.:
Worm   214 SMVSACG--FWGILSHVTFTSNWQSTP--TCMGYLWYLGLDMQLYMVAPIFLNLLHKFPKRGMAL 274

  Fly   466 -VPIVIVLILCLGG---TFATFMLND----FTLFRVQDDQV---------DLRQRLTYYPTHTRI 513
             :..:|..::...|   .:.|...:|    |..:..||.:.         |:     |...:|:.
Worm   275 TITTIIASMVIRAGYCTAYGTCNQSDVDIPFISYPGQDAETLKSIYAGLWDM-----YSRPYTKC 334

  Fly   514 PTWLIGVIFGYFLFTRNRGRQIPMSKPLVLTGWFVAFGTMLACMWGPYWRILPDTPDSPLIEGAF 578
            ..:|||::.||...:.........||.|..:...||..|:.|.: ..||.  |:..::  :....
Worm   335 GPFLIGLLLGYITVSSKYIMVSTTSKTLFRSSLIVAIATIYAIL-PEYWN--PNAGNT--LYNTV 394

  Fly   579 FEPLSRTSWALSIGWIVWACY--------NGHGGLVNDFLSWGFFTGFSRLCYCMYVIHR-IVQL 634
            :..:.|:.:|::|..::.|.|        |            ..|...::|.|..|::|. :|.:
Worm   395 YTAVFRSVFAMAISGMIAALYFRQEYRPTN------------PIFAMLAKLTYNAYLLHMPVVYI 447

  Fly   635 VN-AARLQTDT---HF---SNYDAILRWWHDFGITLTASIFATLAFEAPI 677
            .| ...||..|   |.   ..:.|||        :..|::...|..||||
Worm   448 FNWLPFLQAATSPIHLLLVLPFVAIL--------SFIAALIFYLFIEAPI 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781
		Acyl_transf_3	286..635	CDD:280013	89/418 (21%)
		OafA	289..702	CDD:224748	102/446 (23%)
rhy-1	NP_495954.1	OafA	89..489	CDD:224748	100/450 (22%)
rhy-1	NP_495954.1	Acyl_transf_3	95..479	CDD:280013	97/434 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820