DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3106 and oac-46

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_495886.2	Gene:	oac-46 / 174415	WormBaseID:	WBGene00011768	Length:	676	Species:	Caenorhabditis elegans

Alignment Length:	743	Identity:	181/743 - (24%)
Similarity:	309/743 - (41%)	Gaps:	145/743 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VLLIATAVGAQDTSSNYLLTGHSTPLASSFAHQFFTLASQSAELANRTNTQVIQTYEDRNYDDEL 75
            :||::.|:.:..      |..:..|....|.::     ||:.:|:.:
Worm     7 LLLLSPAIASAG------LEEYDEPFILQFINR-----SQTLDLSLK------------------ 42

  Fly    76 CDRDINLIRDSINNLE---EWALEFPDTWGRLPMGLFWGHTISMGQYEECVAASSTHTTEIRGQY 137
            |.:.:.|:.|.:|::|   :..:.:.:::...|..||.........|              :|..
Worm    43 CKQSLALVYDYLNDIETLTDQKICYFESFATGPNDLFLSRDQDRWVY--------------KGYE 93

  Fly   138 CLASLNITTFYQSVKKRGEEFSRISYKQTDPE---VFELGICVPKTCSAAKTEKLLK--YAITHF 197
            ||.|...|.:.:|     |......|...|.:   |....:|:|..| |.:.:|||:  ..|||.
Worm    94 CLLSAGETVYSKS-----EHPMHYCYTHDDDKDKRVPAFSVCIPSPC-ADENQKLLEEWRRITHP 152

  Fly   198 YGQDVMESNYTMVTEARCK---YDAPIELRGIDIFAIIFFSLIIFFMVASSVYDYIQTRKGAPKK 259
            ...:.:  .:|..|.:|.:   ::.|:.:      |...|::.:..:|..:.  .....:|...|
Worm   153 EATEPI--TFTACTRSRHEKQWFELPVPI------ADFGFNMSLAMLVVMAT--IFHNMRGEDAK 207

  Fly   260 P----LLIAFSVLTNAPKIFTVKKVNNPNVIHCLNGLRCFSMMWVVFGHGYMTFYDLPHINKNKF 320
            .    :|:|||..||..|:..:.| :..:.|.||.|||..||:|.:.||.:: |......|...|
Worm   208 SWSARILLAFSAKTNLKKLIALPK-DPQSCITCLLGLRFGSMVWTLIGHSFI-FVQAYMENVEDF 270

  Fly   321 -YTWVQTPYSMLVQNGSLCVDTFFFMSGLLMCWGAFR-------EMERTKGKLNIPMMYF-HRYI 376
             .:.|...::..:.|.:|.||.|..:.|.::.:..||       |.|.|.......:.:: ||.:
Worm   271 KNSMVDNFFNQWITNFTLSVDVFLTLGGTVLSYSWFRKWLKNTSEEEPTWTSWGYWLKFYRHRVV 335

  Fly   377 RLTPVVAVVVLYIMSLYKYSGAGPMWFKLGTQDK--RCADTWWATLIYVQNYAFPYSI----CIS 435
            ||.|.....:|.:......:...|||   ...|.  :|...||      ||..|..||    |:.
Worm   336 RLYPAYLYTLLAVTLRISVTHFHPMW---PPTDPAIQCPKYWW------QNVLFVNSILDNQCMP 391

  Fly   436 QSWYLAVDTQLYFLSPLFLIPLWKWGKKALVPIVIVLILCLGGTFATFMLNDF--TLFRVQDDQV 498
            .:||:..:...|.|||:||:.|.|..|...:...:|::...|....:.:.|:|  |.|..:..::
Worm   392 WTWYIGTEFIYYLLSPIFLLTLRKAPKIGFILCFVVIMFSAGLNVESIVRNNFPPTQFLWKQPEM 456

  Fly   499 ----DLRQRLTYY--PTHTRIPTWLIGVIFGYFLFTRNRGRQIPM----SKPLVLTGWFVAFGTM 553
                .::..|..|  |.: ||..:|||::.||.|   .|.::||:    |...:::.|.||...:
Worm   457 FNPNFIQHHLELYIKPQY-RIGPYLIGILLGYQL---ARYQRIPVKPQQSNKYIISMWSVALVGI 517

  Fly   554 LACMWGPY----------WRILPDTPDSPLIEGAFFEPLSRTSWALSIGWIVWACYNGHGGLVND 608
            |..::|.|          ||..      .|:.||    |.|..:::.|.::::.|:.|.||.||.
Worm   518 LFGLYGLYPALQGWDSIAWRAY------HLLYGA----LHRDIFSIGIAFLIYICHTGIGGPVNV 572

  Fly   609 FLSWGFFTGFSRLCYCMYVIHRIVQLVNAARLQTDTHFSNYDAILRWWHDFG---ITLTASIFAT 670
            |||..||...:.|.:..|:.|.|..::....:....:|:.  .|..:.|.|.   ||...:|..|
Worm   573 FLSSNFFLPLANLSFSAYLFHMIPVVLTYMLVPFPIYFNT--QIPLFIHCFVQLLITYFFAIICT 635

  Fly   671 LAFEAPILGIEKAIFGKPAPK---KPSP 695
            :..|.|.|.||:.:...| ||   ||||
Worm   636 MVSELPALNIERLLLASP-PKTTLKPSP 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781	28/136 (21%)
		Acyl_transf_3	286..635	CDD:280013	106/385 (28%)
		OafA	289..702	CDD:224748	124/450 (28%)
oac-46	NP_495886.2	OafA	279..653	CDD:224748	104/398 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820