DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3106 and oacyl

DIOPT Version :9

Sequence 1:	NP_001285060.1	Gene:	CG3106 / 31909	FlyBaseID:	FBgn0030148	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	XP_021324686.1	Gene:	oacyl / 100002566	ZFINID:	ZDB-GENE-090710-2	Length:	676	Species:	Danio rerio

Alignment Length:	704	Identity:	174/704 - (24%)
Similarity:	299/704 - (42%)	Gaps:	141/704 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 CDRDINL--IRDSINNLEEWALEFP--------DTWGRLPMGLFWGHTISMGQYEECVAASSTHT 130
            |.|:::|  :.|::..|.|...|.|        |.:|::...:..|:....|...||:   |...
Zfish    21 CARNVSLKCVDDTMGFLMELQKETPSKFAVIMYDAFGKIGSDVEGGNVNRPGSLRECL---SVEG 82

  Fly   131 TEIRGQYCLASLNITTFYQSVKKRGEEFSRISYKQTDPEVFELGICVPKTCSAAKTEKLLKYAIT 195
            ...|||||                     ::..||...|.| :|:|||.:|:.::.:.|    :.
Zfish    83 PGFRGQYC---------------------QVFLKQDKVEYF-VGVCVPDSCTDSEVQTL----VI 121

  Fly   196 H--FYGQ---------DVMESNYTM-VTEARCKYDAPIELRGIDIFAIIFFS----LIIFFMVAS 244
            |  |..|         .::..:.|: :...:|..|:|    .||:.||:..|    |:...::||
Zfish   122 HEAFQKQQMSLLPSVPSILIPDSTLGIFMTQCHSDSP----NIDLSAIVCLSVCCALLALPLIAS 182

  Fly   245 SVYDYI---QTRKGAPKKPLLIAF------SVLTN---------APKIFTVK-KVNNP------- 283
            .....|   |.|:.||...|....      :||||         :|.:.|.: |..|.
Zfish   183 IFVALIKRKQMREVAPVVGLAQTSNSKQYGTVLTNGSANQNKECSPDLDTTQTKTQNAESKQQSL 247

  Fly   284 -----------NVIHC----------------LNGLRCFSMMWVVFGHGYMTFYDLPHINKNKFY 321
                       :|.:|                |||:|..|:.|::.|| .:.|....|::..|
Zfish   248 SKTVVSWLQGFSVQNCSQGLLDTEGSGRSYSSLNGIRILSLFWIISGH-TVHFSAWSHLDNEK-- 309

  Fly   322 TWVQ----TPYSMLVQNGS--LCVDTFFFMSGLLMCWGAFREMERTKGKLNIPMM---YFHRYIR 377
            .|.:    .|..:|..:|.  |.||:|..:.|||........:.|:...|::.::   .|.|:.|
Zfish   310 RWKEMVENNPLYVLTFSGPVYLAVDSFLVLGGLLSAKSLLGTIRRSDNTLSVGLVVNYLFKRFKR 374

  Fly   378 LTPVVAVVVLYIMSLYKYSGAGPMWFKLGTQDKRCADTWWATLIYVQNYAFPYSICISQSWYLAV 442
            :.|:...:|..::||:.....|..||....|...|...||:.|:.:.|......||...:|||::
Zfish   375 IQPLHLFIVCLVISLFSVVPRGVFWFFAEDQVLSCKKYWWSNLLLINNLLTITDICAPWTWYLSI 439

  Fly   443 DTQLYFLSPLFLIPLWKWGKKALVPIVIVLILCLGGTFATFMLNDFTLFRV-QDDQVDLRQRLTY 506
            |.|.|..:|| ||.|::..|.|||.:.:||::....|.|  ::..|....| |...:.......|
Zfish   440 DFQFYATTPL-LIFLYRMNKCALVVVSVVLLMLSSVTGA--LITSFLHLPVHQPTTLAYESYFQY 501

  Fly   507 Y--PTHTRIPTWLIGVIFGYFLFTRNRGRQIPMSKPLVLTGWFVAFGTMLACMWGPYWRILPDTP 569
            |  ..:||...:|:||:.|.::.|:...  :...:...:.||..:...|...:...|  :|.|.|
Zfish   502 YYNKPYTRYGPYLLGVLAGIYMTTKKEA--LIKHQWQAVIGWLCSLSVMALLVGLAY--VLRDVP 562

  Fly   570 DSPLIEGAFFEPLSRTSWALSIGWIVWACYNGHGGLVNDFLSWGFFTGFSRLCYCMYVIHRIVQL 634
            ....|..|.::.:.|:.|||::.||:.||..|:||.|:.|||...:...|.:.:..|:||.|:.:
Zfish   563 PHLSIPHAIYQGIHRSLWALALIWIILACEEGYGGFVDTFLSLSLWAPLSNISFACYLIHPIIII 627

  Fly   635 VNAARLQTDTHFSNYDAILRWWHDFGITLTASIFATLAFEAPILGIEKAIFGKP 688
            :...:.:...|:::::    :::.|...|..|||  :.:...:| |||....:|
Zfish   628 LYNGKQEITMHYTDFN----FFYLFLGHLVLSIF--IGYVLTVL-IEKTYLFQP 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3106	NP_001285060.1	NRF	91..217	CDD:214781	30/145 (21%)
		Acyl_transf_3	286..635	CDD:280013	103/376 (27%)
		OafA	289..702	CDD:224748	113/412 (27%)
oacyl	XP_021324686.1	NRF	48..120	CDD:214781	22/100 (22%)
oacyl	XP_021324686.1	OafA	273..668	CDD:224748	110/411 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588173
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.700