Protein Alignment Ptpmeg2 and PTP1

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_010051.1
• Gene: PTP1 / 851368
• SGDID: S000002389
• Length: 335
• Species: Saccharomyces cerevisiae
• Alignment Length: 342
• Identity: 102/342 - (29%)
• Similarity: 156/342 - (45%)
• Gaps: 91/342 - (26%)

  Fly   525 VKQR-----GRHGLIKEYADIRNR-APEGTFLHARMR-------ANLTKNRYTDVLCYDHSRVVL 576
            ::||     |:...|:...|.|.| |..|| :::|..       .|..:|||.:::.|:.:||.|
Yeast     8 IRQRDTDLLGKFKFIQNQEDGRLREATNGT-VNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHL 71

  Fly   577 AHEDGDEPSDYINANFV----------DGYKQKNAYISTQGPLPKTSQDFWRMIWEQHC----LV 627
            ....|   :|||||::|          .||     ||:||||..||...||:|.: .:|    :|
Yeast    72 KTLSG---NDYINASYVKVNVPGQSIEPGY-----YIATQGPTRKTWDQFWQMCY-HNCPLDNIV 127

  Fly   628 IVMTTRVMERGRVKCGQYW----------------EPTEESSL-EF-GDYHVRTISVECNEDYMV 674
            |||.|.::|..|.||.|||                .|...:.: :| .|..:..::|...:||..
Yeast   128 IVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYT 192

  Fly   675 ASLELRNIKTD----EIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGH 735
            .: :::...||    .::.|.|:.|..|.|...|              |:...:::....:.:.:
Yeast   193 VT-DIKLTPTDPLVGPVKTVHHFYFDLWKDMNKP--------------EEVVPIMELCAHSHSLN 242

  Fly   736 PRGPPIVVHCSAGIGRTGTFITLDICI------------SRLEDVGTAD-IRGTVEKI----RSQ 783
            .||.||:||||||:|||||||.||..:            ||..|..|.: .|..:|:|    |||
Yeast   243 SRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQ 307

  Fly   784 RAYSIQMPDQYVFCHLA 800
            |...:|..||::|.:.|
Yeast   308 RMKMVQTKDQFLFIYHA 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	99/330 (30%)
PTP1	NP_010051.1	PTP_fungal	79..323	CDD:350509	80/264 (30%)