DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and PTP1

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_001031266.1	Gene:	PTP1 / 843516	AraportID:	AT1G71860	Length:	340	Species:	Arabidopsis thaliana

Alignment Length:	358	Identity:	118/358 - (32%)
Similarity:	180/358 - (50%)	Gaps:	59/358 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   471 AAGAAGAAAGTTTNGGGEF---WSENPPSSASSGFSDD------DSLAGQEGDPKPIDQIVQMVK 526
            |.|...:||...| |...|   .:::|||..|  .|.|      .:|....|..:..|.|..
plant     2 ATGKTSSAANLFT-GSTRFDLSSADSPPSKLS--LSSDQLNHCHQALGVFRGKIQNPDSIAH--- 60

  Fly   527 QRGRHGLIKEYADIR-NRA-PEGTFLH---ARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSD 586
                     |:..:: ||. |....|:   |....|:.||||:||:.:|.:|:||..........
plant    61 ---------EFTGLQANRMWPSELLLNSTVAMNSVNVEKNRYSDVVPFDKNRIVLNPCKDSSAKG 116

  Fly   587 YINANFVDGYKQK--NAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGR-VKCGQYWEP 648
            |:||:.:...:.:  :.:|:||||||.|.:|||.|:.:|||.:|||.||:::..| ||||.|::
plant   117 YVNASLIKTSESESISQFIATQGPLPHTMEDFWEMVIQQHCPIIVMLTRLVDNNRTVKCGDYFQ- 180

  Fly   649 TEESSLEFGDYHVRTISVECNEDYMVASLELRNIKT------DEIRNVSHWQFTSWPDYGVPSSA 707
            .|:...|||:..:.|..::..:    .||.|||::.      |:..:|.|.|:..|||:|||...
plant   181 DEDGPREFGNISLTTKWIKTTD----TSLMLRNLEVNYKETEDQPMSVLHIQYPEWPDHGVPKDT 241

  Fly   708 MAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRL--EDVGT 770
            :|:...|:::    .|:...||          ||:||||||||||||:..:...|.|:  .|:..
plant   242 VAVREILKRL----YQVPPSLG----------PIIVHCSAGIGRTGTYCAIHNTIQRILAGDMSA 292

  Fly   771 ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE 803
            .|:..||...|.||...:|..|||.||:.|:::
plant   293 LDLAKTVALFRKQRIGMVQTMDQYFFCYNAIVD 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	95/256 (37%)
		PTPc	559..803	CDD:238006	94/254 (37%)
PTP1	NP_001031266.1	PTPc_plant_PTP1	117..321	CDD:350496	83/222 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	163	1.000	Domainoid score	I1235
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000704
OrthoInspector	1	1.000	-	-		otm2866
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19134
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3336
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.010