Protein Alignment Ptpmeg2 and PTPRE

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_047281532.1
• Gene: PTPRE / 5791
• HGNCID: 9669
• Length: 733
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 119/303 - (39%)
• Similarity: 165/303 - (54%)
• Gaps: 35/303 - (11%)

  Fly   515 PKPIDQIVQMVKQRGRHGLIKEYADIRNRAP----EGTFLHARMRANLTKNRYTDVLCYDHSRVV 575
            |.|::.:.:.::.|.... .|::.:..|..|    :|||..|....|..||||.::|..|||||:
Human   147 PIPVEHLEEEIRIRSADD-CKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVI 210

  Fly   576 LAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRV 640
            |:..||...||||||:::||||:||.:|:.|||..:|..|||||:|||....|||.|.:.||...
Human   211 LSQLDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEE 275

  Fly   641 KCGQYWEPTEESSLEFGDYHVRTISVECNE------DYMVASLELRNIKTDEI---RNVSHWQFT 696
            ||.|||  .::....:|:..|      |.|      ||.:....::....|..   |.||...||
Human   276 KCHQYW--PDQGCWTYGNIRV------CVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHFT 332

  Fly   697 SWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDIC 761
            ||||:|||.:.:.||.||:||:.        |....||     |||||||||:|||||||.:|..
Human   333 SWPDFGVPFTPIGMLKFLKKVKT--------LNPVHAG-----PIVVHCSAGVGRTGTFIVIDAM 384

  Fly   762 ISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY 804
            ::.:......|:...|.:||:||...:|...||.|.:.||:||
Human   385 MAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEY 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	112/282 (40%)
PTPRE	XP_047281532.1	R-PTPc-E-1	198..426	CDD:350468	103/248 (42%)
		R-PTPc-E-2	513..722	CDD:350470