Protein Alignment Ptpmeg2 and PTPN2

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_047293651.1
• Gene: PTPN2 / 5771
• HGNCID: 9650
• Length: 494
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 110/292 - (37%)
• Similarity: 158/292 - (54%)
• Gaps: 41/292 - (14%)

  Fly   539 DIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYI 603
            :|||.:.:.....|:...|..:|||.||..||||||.|.:.:    :|||||:.||..:.:.:||
Human   108 EIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYI 168

  Fly   604 STQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGD--YHVRTISV 666
            .||||||.|...||.|:|:|....:||..|::|:..|||.||| ||::..:.|.:  :.|:.:|.
Human   169 LTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYW-PTDDQEMLFKETGFSVKLLSE 232

  Fly   667 ECNEDYMVASLELRNI-----------------------KTDEIRNVSHWQFTSWPDYGVPSSAM 708
            :....|.|..|:|.||                       |:.|.|.:||:.:|:|||:|||.|..
Human   233 DVKSYYTVHLLQLENINYIENLWITLYLKLLMLDVKRSLKSGETRTISHFHYTTWPDFGVPESPA 297

  Fly   709 AMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADI 773
            :.||||.||||..:.           :|...|.|:||||||||:|||..:|.|:..:|.....:|
Human   298 SFLNFLFKVRESGSL-----------NPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINI 351

  Fly   774 RGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA 805
            :..:..:|..|...||.|||..|.::|:||.|
Human   352 KQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGA 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	106/284 (37%)
PTPN2	XP_047293651.1	PTP_DSP_cys	108..379	CDD:475123	106/286 (37%)