Protein Alignment Ptpmeg2 and ca16b

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_021332937.1
• Gene: ca16b / 569183
• ZFINID: ZDB-GENE-080818-1
• Length: 1382
• Species: Danio rerio
• Alignment Length: 1043
• Identity: 245/1043 - (23%)
• Similarity: 379/1043 - (36%)
• Gaps: 342/1043 - (32%)

  Fly    44 IDLCNNLGANCSTTTATSPSTSSSSASSTQN---LIAVV------------PPQLQQLQVQLPAP 93
            :|....:...|...|.....|.||:.::.:|   .:::|            |.:.:..:|:.  .
Zfish    84 LDPETQVSQECQELTLDGFETKSSNRTTMKNTGKTVSIVLKNDYFVRGAGLPGRFKAEKVEF--H 146

  Fly    94 GGGGGAGAGGGGGGGGGAAPVRRHI---------SHTTAVKFLYARKFDIPRAVSLYEQHEQIRL 149
            .|.....||......|...||...|         |.:||:|   .|:.....||..     |:..
Zfish   147 WGSTNGSAGSEHSINGKKFPVEMQIYFYNSDDFDSLSTAIK---ERRIIAAMAVFF-----QVAT 203

  Fly   150 KEYLYNI--DPDVEPLR------SELQTGKFTILPARTSSGAAIALFTANRHSP----------- 195
            |:   ||  :|.:..|:      .|...|.|.:.....||..:...:|.:..:|
Zfish   204 KD---NIAAEPIIAGLKRVVHHEKETNLGSFILRDLLPSSLGSYYRYTGSLTTPPCSKVVEWIIF 265

  Fly   196 -----LSVSH--------TTTLQGIVYQLD------SALQDSETQRAGLVFIYD--MSGSKYSNF 239
                 ||...        ||..|..|..:|      ..:||.:::|.....:.|  |..:..|..
Zfish   266 SRPVYLSYHQLEAFYSIFTTEQQDHVKSVDYLRNNHRPIQDLDSRRIFKSALMDAWMPETMASAA 330

  Fly   240 DYDLSQKILTLLKGGYPARLK------KVLIVTAPLW------FKAP---FKILRLFVREKLR-E 288
            |.:.|:...::     |..:|      ..|::|   |      :..|   |.:...:|::::. |
Zfish   331 DTETSRVCSSI-----PDNMKLHPLNRTALVLT---WDRPSAVYHPPIVGFLVSYSWVKDEMPFE 387

  Fly   289 RVFTVSVPQLALHVPRKALPIHLGGTLEVDHATWL-----LSCRQSMTNREDELL--ANIVGVGG 346
            :.||    |.:.|..|..:      ||......:|     |..|...::....||  ||...:..
Zfish   388 KTFT----QSSEHSTRAVI------TLVSPDVLYLFRVQALCQRDQRSDFSQTLLFKANTTRIFE 442

  Fly   347 GS----------GSGSAAGSAAIVSTNGTETEAATTAATIISAVHQLGDNNTTVVTVSNGVGPAG 401
            |:          ...|:|..|.|.|.:.|.|.|...               .:.|:::.|:||
Zfish   443 GTRIVKTGMPTVSPASSADMAPISSGSSTWTSAGLP---------------FSFVSMATGMGP-- 490

  Fly   402 SASGGATTAASAATE---------------------PNENITINGLSPSHRQA---ANNSSSSSS 442
            .:|||..|.||..|.                     |..: |..|.||:...|   |.||.|..|
Zfish   491 PSSGGQATVASVVTSTLLAGLGFSGSVISSLPGSFWPTHS-TNTGPSPTQHPATPTAENSPSEDS 554

  Fly   443 S----------------------------------------------AATVANP-LKLNTSGSAD 460
            :                                              ..||..| ..:.||...|
Zfish   555 TDTQNKLEEEEEHKKEDDEEEEEEEEEEEQRDEEKKKKGKDVTVKDKKQTVQKPTAPIPTSKHRD 619

  Fly   461 ------NNSTITNATTAAGAAGAAAGTTTNGGGE-FWSEN-----PPSSA-SSGFSDD------- 505
                  .:||:|.|......:||..........: .|.::     |.||. ||..||:
Zfish   620 RERPDAESSTLTPAEVEEQVSGATERPDAEDSSKATWQDDNDMQIPSSSTESSKLSDEEKANWPY 684

  Fly   506 --------------DSLAG-------------------------------------------QEG 513
                          ||::.                                           ...
Zfish   685 YINTERNSISTVSRDSVSSSSRMEWIIPLMVVSALTLLCLIMLLAVLVYWRRFFQTAHFYIEDRN 749

  Fly   514 DPK-------------------PIDQIVQMVKQ---RGRHGLIKEYADIRNRAPEG--TFLHARM 554
            .|:                   |:.|.::.:.:   ..|||..:|:.::::...|.  |..|:..
Zfish   750 SPRVIHNDSFPIISTADDLEAMPVRQFIKHIMELHSNNRHGFSQEFDEVQHCTSEMKITAEHSNH 814

  Fly   555 RANLTKNRYTDVLCYDHSRVVLAHEDGDEP--SDYINANFVDGYKQKNAYISTQGPLPKTSQDFW 617
            ..|..||||.:::.||||||.|....|.:.  |||||||:|||||:..|||:.||||..|.:|||
Zfish   815 PENKHKNRYINIVAYDHSRVKLQQLPGKDSKHSDYINANYVDGYKRARAYIAAQGPLKSTFEDFW 879

  Fly   618 RMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNI 682
            ||||||:..||||.|.::|:||.||.||| |:|.|.: :|:..|...|.:....|.:....:||.
Zfish   880 RMIWEQNTTVIVMITNLVEKGRRKCDQYW-PSENSEV-YGNIMVTLKSTKVYAYYTLRHFIVRNS 942

  Fly   683 K-------TDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPP 740
            |       ....|.|..:.:|.|||.|||...:.:|.|:.:.....|...             .|
Zfish   943 KLKKGQKGRQNERLVLQYHYTQWPDMGVPEYTLPVLKFISRSTVTHASST-------------GP 994

  Fly   741 IVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA 805
            ::||||||:|||||:|.:|..:.:::|.|:.::.|.::.||.||.|.:|..:|::|.|.||:|..
Zfish   995 VLVHCSAGVGRTGTYIVIDSMLKQIKDRGSVNVLGFLKHIREQRNYLVQTEEQFIFIHDALMEAV 1059

  Fly   806 YSR 808
            .|:
Zfish  1060 LSK 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	9/38 (24%)
		SEC14	170..314	CDD:469559	35/191 (18%)
		PTPc-N9	529..799	CDD:350391	109/280 (39%)
ca16b	XP_021332937.1	alpha_CARP_receptor_like	62..314	CDD:239396	47/242 (19%)
		FN3	340..417	CDD:214495	17/94 (18%)
		PTP_DSP_cys	791..1060	CDD:475123	110/283 (39%)
		R-PTP-G-2	1144..1348	CDD:350508