Protein Alignment Ptpmeg2 and ptprt

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_021332968.1
• Gene: ptprt / 567095
• ZFINID: ZDB-GENE-101028-4
• Length: 1508
• Species: Danio rerio
• Alignment Length: 957
• Identity: 234/957 - (24%)
• Similarity: 358/957 - (37%)
• Gaps: 281/957 - (29%)

  Fly    56 TTTATSPSTSSSSASSTQNLIAVVPPQLQQLQVQLPAPGGGGGAGAG-------------GGGGG 107
            |||.....|....| .|..|..:.|....:::|.|..||.||....|             .|...
Zfish   325 TTTGNWAETHVVDA-PTYKLWHLDPDVEYEIKVLLTRPGEGGTGPPGPPLITRTKCADPVNGPQN 388

  Fly   108 GG----------------GAAPVRRHISHTTAVKF-------LYARKFDIPRAVSLY-----EQH 144
            ..                |.|..|.| |....|::       :||.:..||.: |.|     ...
Zfish   389 VNVVDIRARQLTLQWETFGYAVTRCH-SFNLTVQYQYVFNQQVYATEDLIPTS-SHYTLRGLRPF 451

  Fly   145 EQIRLKEYLYNID----------------PDVEPLRSELQTGK-----FTILPARTSSGAAIALF 188
            ..:||:..|.|.:                |...|:.| :|||.     |....|...:...|.|:
Zfish   452 VTVRLRLVLANPEGSKESEEIVKQTEEDVPGPIPMES-IQTGPYEEKIFMQWKAPNETNGVITLY 515

  Fly   189 TANRHSPLSVSHT---TTLQGIVYQLDSALQDSETQR------AGLVFIYDMSGSKYSNFDYDLS 244
            .....:..|:..|   ||.:|.|::|     .:||..      .|..:.:.:..|....|...::
Zfish   516 EIAYKALSSLDPTADLTTQRGRVFKL-----QNETHHLFVGLYPGTTYFFTLKASTNKGFGPPVT 575

  Fly   245 QKILT-------------------------LLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVRE 284
            .:|.|                         |||   ||:.:           .||....::.|:|
Zfish   576 TRITTKIAAPSMPEYETDSPLNETDTTITVLLK---PAQSR-----------GAPVSSYQVVVQE 626

  Fly   285 KLRERV---------------------------FTVSVPQLALHVPRKALPIHLGGTLEVDHATW 322
            :.:::|                           |...:|.::|.|.:   |..:|     |:.|:
Zfish   627 ERKQKVRRATDVLECFPVPVSFRNASILDSPHYFAAELPPVSLAVVQ---PFTIG-----DNKTY 683

  Fly   323 -------LLSCRQ--------SMTNREDEL----LANIVGVGGGSGSGS-----AAGSAAIVSTN 363
                   |...:.        |..|.|.::    ||..|.:|.|..:..     .:..|:..::|
Zfish   684 NGYWNAPLSPAKSYSIYFQALSKANGETKINCVRLATKVVIGRGQNTTPYILVIPSEGASTQNSN 748

  Fly   364 GTETE---------AATTAATIISAVHQLG----------------------------------D 385
            ..|.|         |...|..::..:..||                                  .
Zfish   749 DIEPEKQVDSTVKMAGVIAGILMFVIILLGLLLTFKRREIHTWRTLSVGRNAYSYSYYLKLAKKQ 813

  Fly   386 NNTTVVTVSNGVGPAGSA---SGGATTAASAATEPNENITINGLSPSHRQAANNSSSSSSSAATV 447
            ..|...:....:||.|:|   :|..:|..........|..:||.|.|
Zfish   814 KETASSSTQREMGPVGTADKSTGKVSTLHKDDPFSTSNQDLNGFSSS------------------ 860

  Fly   448 ANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASS----GFSDDDSL 508
             :|...:..|.|..:.|:.|:..:.......|..:.:|.....|:  ||....    |..:...:
Zfish   861 -SPCSFSIQGKAIQSKTLLNSYYSVSKEPVPATASIDGSHSEMSQ--PSMTIQTYPYGGCESVEM 922

  Fly   509 AGQEGDPKP-------IDQIVQMVKQRGRHGLIKEYADIR--NRAPEGTFLHARMRANLTKNRYT 564
            :.|.|..:|       :..|.||...:| :|..:||..:.  ..||..|   |:...|..||||.
Zfish   923 SYQAGQFQPAIRVADLLQHITQMKCGQG-YGFKEEYEGLAEGQTAPWET---AKKEENRNKNRYG 983

  Fly   565 DVLCY---DHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCL 626
            :::.|   ||:||.|...:||..|||||||::|||.:...||:||||:.:|.:|||||||:::..
Zfish   984 NIIAYPTDDHTRVRLQPLEGDPHSDYINANYIDGYHRPRHYIATQGPMQETVRDFWRMIWQENSA 1048

  Fly   627 VIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVS 691
            .|||.|.::|.|||||.:||....|   .:||..|..|..|...:|::.:..::.....|||.:.
Zfish  1049 SIVMVTNLVEVGRVKCVRYWPDETE---VYGDIKVTLIETEPLAEYVIRTFTVQKKGHHEIREIR 1110

  Fly   692 HWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFI 756
            .:.||||||:|||..|..:|.|:::|:             :...|...|||||||||.||||.||
Zfish  1111 QFHFTSWPDHGVPCYATGLLGFIRQVK-------------FLNPPDAGPIVVHCSAGAGRTGCFI 1162

  Fly   757 TLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE 803
            .:||.:...|..|..||...:.::||||...:|..:||||.|.|::|
Zfish  1163 AVDIMLDMAESEGVVDIFNCIRELRSQRVNMVQTEEQYVFVHDAILE 1209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	10/41 (24%)
		SEC14	170..314	CDD:469559	35/209 (17%)
		PTPc-N9	529..799	CDD:350391	111/274 (41%)
ptprt	XP_021332968.1	MAM	24..185	CDD:214533
		FN3	226..733	CDD:442628	83/438 (19%)
		FN3	285..356	CDD:214495	8/31 (26%)
		FN3	386..476	CDD:238020	16/91 (18%)
		fn3	498..573	CDD:394996	16/79 (20%)
		R-PTPc-T-1	974..1213	CDD:350478	106/252 (42%)
		R-PTPc-T-2	1298..1503	CDD:350482