Protein Alignment Ptpmeg2 and Ptpn9

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_062625.2
• Gene: Ptpn9 / 56294
• MGIID: 1928376
• Length: 593
• Species: Mus musculus
• Alignment Length: 694
• Identity: 269/694 - (38%)
• Similarity: 360/694 - (51%)
• Gaps: 154/694 - (22%)

  Fly   118 ISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRSELQTGKFTILPARTSSG 182
            :|...|||||.|||||:.|||.|:..:.:.|.||.:..:.|..||||||:.:||||||..|..:|
Mouse    42 LSWNVAVKFLMARKFDVLRAVELFHCYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTG 106

  Fly   183 AAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYDLSQKI 247
            |:||||||..|.|...:....||.:.|.||.|:...||||.||||||||.||.|:||:.||.:|:
Mouse   107 ASIALFTARLHHPHKSAQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKV 171

  Fly   248 LTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKALPIHLG 312
            |.||||.:||||||||||.||:||:.|:.|:.|.:::|:|||:..:...::..|:||:.||.:||
Mouse   172 LNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLG 236

  Fly   313 GTLEVDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEAATTAATII 377
            |.:::|.|||
Mouse   237 GYVKIDLATW------------------------------------------------------- 246

  Fly   378 SAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSSSSSS 442
                     |...:...||                 ..:|.:.|.::.|.|:
Mouse   247 ---------NFQFLPQVNG-----------------HPDPFDEIILSSLPPA------------- 272

  Fly   443 SAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDDS 507
                                                                        .|.||
Mouse   273 ------------------------------------------------------------LDWDS 277

  Fly   508 LAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHS 572
            :.........|.::|..|..|.:.|:.:||.|||...|.|||..:....||.||||.||.|.|.:
Mouse   278 VHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQT 342

  Fly   573 RVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMER 637
            ||.|....|...:|||||:|:||||||||||.|||||..|.:|||.|:|||..||||||||..|.
Mouse   343 RVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEG 407

  Fly   638 GRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYG 702
            ||.||||||...::|.:.||...|..:.||....|...:||:.|.:..:.|.|:|:||.||||||
Mouse   408 GRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYG 472

  Fly   703 VPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLED 767
            |||||.::::||:.||.:|:..|..||....|....|||||||||||||||||.:||||:::||:
Mouse   473 VPSSAASLIDFLRVVRNQQSMAVGNLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEE 537

  Fly   768 VGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGML 811
            :||.::..||.::|:|||:|||.|:||.||:.|::|:|...||:
Mouse   538 LGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMV 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	15/25 (60%)
		SEC14	170..314	CDD:469559	76/143 (53%)
		PTPc-N9	529..799	CDD:350391	144/269 (54%)
Ptpn9	NP_062625.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		CRAL_TRIO_N	20..66	CDD:215024	15/23 (65%)
		SEC14	90..240	CDD:214706	78/149 (52%)
		PTPc-N9	299..569	CDD:350391	144/269 (54%)