Protein Alignment Ptpmeg2 and ptpn9b

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_690659.6
• Gene: ptpn9b / 562170
• ZFINID: ZDB-GENE-090313-52
• Length: 754
• Species: Danio rerio
• Alignment Length: 762
• Identity: 342/762 - (44%)
• Similarity: 445/762 - (58%)
• Gaps: 90/762 - (11%)

  Fly   118 ISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRSELQTGKFTILPARTSSG 182
            :|..||||||.|||||:.||:.|::.::..|:||.:|||:|:.|||||||.:||||:||.|.:.|
Zfish    31 VSQMTAVKFLMARKFDVSRAIDLFQAYKNTRIKEGIYNINPNEEPLRSELLSGKFTVLPGRDAKG 95

  Fly   183 AAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYDLSQKI 247
            ||:|||||..|.|...:|...||.|:||||.|::..:|||.||:|||||:.|.|:||||:|..||
Zfish    96 AALALFTARLHQPDRTTHKAVLQAIIYQLDKAIESVQTQRDGLIFIYDMTNSTYANFDYELCVKI 160

  Fly   248 LTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKALPIHLG 312
            |.||||.:|||||.|.||::||||:|||.:|||||||||||||.||...:|..|:|..:||.|||
Zfish   161 LNLLKGAFPARLKCVFIVSSPLWFRAPFAVLRLFVREKLRERVCTVKAHELVNHIPVSSLPEHLG 225

  Fly   313 GTLEVDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETE---AATTAA 374
            |:.:..|..|:.||..|..|..:    |...|.|.. .||...|.::.....|..:   |.|:||
Zfish   226 GSSQYSHIAWIQSCVNSSPNHPN----NSAYVTGDC-LGSLLCSYSMEHDQNTSADPLTAKTSAA 285

  Fly   375 TIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAAN---N 436
            |.      |||                    |..:......|.|.|:      |:||...:   |
Zfish   286 TF------LGD--------------------GLNSNCPILDENNANV------PNHRMTGHAHWN 318

  Fly   437 SSS--SSSSAATVAN------PLKLNTSGSADNNSTITNATTAAGAAGA---AAGTTTNGGGEFW 490
            .|:  |..|.|.|.|      |.:.:|......:...|......|..||   |:....||..|..
Zfish   319 GSALPSLGSNANVLNGRGRQPPPQSDTPPDTPLHQKHTAGGGILGVGGACLDASRQDGNGAEESQ 383

  Fly   491 SE---------------------NPPSSASSGFSDDDSLAGQ------------EGDPKPIDQIV 522
            .:                     .||....|...|...|.|.            |.....:..:|
Zfish   384 QDVELLEDEMGEGDGVPPLPLKSRPPPLNHSPTPDMSWLPGMLTETTMLSVHVAEPGGMSVQDLV 448

  Fly   523 QMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLA--HEDGDEPS 585
            |.||::.:.|:.:||.:||...|.|||.:::..:|..||||:||||.|.|||.|.  :::.||.|
Zfish   449 QHVKRKKKKGIYQEYEEIRKEPPAGTFDYSKKASNQIKNRYSDVLCLDQSRVHLCPLNDEDDETS 513

  Fly   586 DYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTE 650
            |||||:|:||||..||||:||||||||..|||||:|||..|:|||||||:|||||||||||....
Zfish   514 DYINASFMDGYKWSNAYIATQGPLPKTFGDFWRMVWEQMVLIIVMTTRVVERGRVKCGQYWPLEA 578

  Fly   651 ESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQ 715
            ..:.|:|.:.||.:.:|..:|:.::.|||.|.:|.|.|.|||:.:.||||:|||.||.|||:|..
Zfish   579 GRTEEYGYFLVRNVHIEVFQDFKLSHLELFNTQTGECREVSHYLYMSWPDFGVPKSASAMLDFRA 643

  Fly   716 KVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKI 780
            .|:.:|...::.|...|.|.|.|||:||||||||||||||.|||||:|||||:||.||:.||.::
Zfish   644 HVKHRQESSLRTLYPDWTGPPGGPPVVVHCSAGIGRTGTFCTLDICLSRLEDIGTVDIKQTVRRM 708

  Fly   781 RSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDLAGFDEREPDSE 827
            |:|||:|||..|||.||:.|:|||....|:||.|:.:. .|.|.|||
Zfish   709 RTQRAFSIQTWDQYYFCYKAVIEYGQQSGLLQPVEWSD-TELETDSE 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	15/25 (60%)
		SEC14	170..314	CDD:469559	88/143 (62%)
		PTPc-N9	529..799	CDD:350391	155/271 (57%)
ptpn9b	XP_690659.6	None