Protein Alignment Ptpmeg2 and ptprc

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_073793929.1
• Gene: ptprc / 559154
• ZFINID: ZDB-GENE-050208-585
• Length: 1542
• Species: Danio rerio
• Alignment Length: 980
• Identity: 239/980 - (24%)
• Similarity: 354/980 - (36%)
• Gaps: 316/980 - (32%)

  Fly    15 NNNSGSRSEQDSGCHRRLFLCIAKAVKQFIDLCN---NLGANCSTTTATS---PSTSSSSASSTQ 73
            |||..:.....|        |.::.......:||   |..||..||||.:   ||.|.:|...::
Zfish   276 NNNKANPPTSPS--------CTSQQNTTNTSVCNTERNNQANTPTTTALTSQQPSNSDTSGLPSR 332

  Fly    74 NLI------------AVVPPQLQQLQVQLPAPGGGGGAGAGGGGGGGGGAAPVR-----RHISHT 121
            .::            ..:||.:..:|...|.|                   ||:     ..||..
Zfish   333 TIMQQHVIITTPVNDTSLPPNITLMQPTSPIP-------------------PVKTTSMGAKISEE 378

  Fly   122 TAVKFLYARKFD-------IPRAVSLYE-QHEQIRLKEYLYNIDPDVEPLRSELQTGK----FTI 174
            |....:...:.:       ||.....|: |...|:||.....|...:.||:..|:..|    :||
Zfish   379 TCQYNITWNETEAIINVSSIPNNARDYKNQTYIIKLKHNTETISNGISPLKIPLKMLKPCTEYTI 443

  Fly   175 LPARTSSGAAIALFTANRHSPLSVSH--TTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYS 237
                                     |  ..|::|                         ..|.||
Zfish   444 -------------------------HVDNCTVKG-------------------------KNSFYS 458

  Fly   238 NFDYDLSQKILTLLKGGYPARLKKVLIVTAPLW-------FKAPFKILRLFVREKLRERVFTVSV 295
            |   |...|..|.:..|     .|.:......|       ..|....::..:...|.:.::.:.|
Zfish   459 N---DSESKEYTAIDVG-----DKQVCFEDKKWNLTGCANITAEDSCVQRSIEINLDKCIYAMKV 515

  Fly   296 ------PQLALHVPRKALPIHLGGTLEVDHATWLLSCRQSMTNREDELLANIVGVGGG------- 347
                  |:|..:   |.:|.....:.:..:.|.:..|..:..          :..|||
Zfish   516 LMPPVKPELKYN---KTIPTKFEWSNKPLNKTRMSDCNDTFE----------IDCGGGKCWRLNQ 567

  Fly   348 ------SGSGSAAGSAAIVST--NGTET--------------EAATTAATIISAVHQLGDNNTTV 390
                  ..|.|..|.....:|  |.|.|              ||.|..:.:||.:...|||...:
Zfish   568 DAYLAPGKSYSCTGKYKYYNTFVNSTSTDILISCNWSYTNLYEAVTNNSIVISRILNPGDNCPGI 632

  Fly   391 V------TVSNGVGPAGSASGG-----ATTA------ASAATE------PNENITING------- 425
            :      |..:..|.|.|...|     |||.      .||.||      .:.|.||.|
Zfish   633 IWHSFSATCQSESGKASSPVHGCDKINATTVNCTFNELSAYTEYKCSISAHINSTIGGEPFVTRF 697

  Fly   426 ------LSP--SHRQAANNSSSSSSSAATVANPL--------------KLNTSGSAD--NNST-- 464
                  ..|  ..::..|.|..|.:|.......|              :|.:||:.:  |||.
Zfish   698 IQRTKSYKPMFGDKKDVNVSGRSHNSFLVNCKNLTETQWNGPRGLYQFELTSSGNTNKYNNSINC 762

  Fly   465 ---------ITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDDSLAG---------- 510
                     :||.|...        |..||.|::   :..|:::|...:|.::.|
Zfish   763 SFLFENLYYLTNYTIKI--------TAINGHGKY---SIVSTSTSTRYNDTAVIGFLAFLIVVTS 816

  Fly   511 -------------------QEGDPKPIDQIVQMVKQRGRHGLI---------------KEYADIR 541
                               .|.|...:.|.::.|:.....|||               .|:..|.
Zfish   817 IALLFVLYKIFLLKRKRRTPEEDEICLTQPLRRVEPIYPEGLIDAYRTKIADESRLFMDEFQSIP 881

  Fly   542 NRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQ 606
            ......|...|:...|.:||||.|:|.||::||.|:   .....|||||:|::||::...||:.|
Zfish   882 RIFNNYTIKEAKRPENQSKNRYVDILPYDYNRVTLS---SGAYGDYINASFIEGYQEPKKYIAAQ 943

  Fly   607 GPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNED 671
            ||..:|..|||:|:|||...:|||.||..|..:|||.|||...:..:..|.|:.|:..:.|...|
Zfish   944 GPKDETIVDFWQMMWEQKSSIIVMVTRCEEGNKVKCAQYWPCLDRETEIFDDFVVKIKTEEHCPD 1008

  Fly   672 YMVASLELRN--IKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAG 734
            |::..|.|.|  .|..| |.::|.||.||||:|||:....:|    |:|.:    |....:.::|
Zfish  1009 YIIRHLVLANKREKASE-REITHIQFISWPDHGVPTDPGQLL----KLRRR----VNSFKNFFSG 1064

  Fly   735 HPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHL 799
                 |||||||||:|||||:|.:|..|..||.....||.|.|.|:|.||...:|:..||:..|.
Zfish  1065 -----PIVVHCSAGVGRTGTYIGIDAMIESLEAENRVDIYGFVAKLRRQRCLMVQVEAQYILIHT 1124

  Fly   800 ALIEY 804
            ||||:
Zfish  1125 ALIEH 1129

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	7/42 (17%)
		SEC14	170..314	CDD:469559	23/162 (14%)
		PTPc-N9	529..799	CDD:350391	109/286 (38%)
ptprc	XP_073793929.1	None