Protein Alignment Ptpmeg2 and ptprz1b

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_073803012.1
• Gene: ptprz1b / 553019
• ZFINID: ZDB-GENE-050506-100
• Length: 1457
• Species: Danio rerio
• Alignment Length: 762
• Identity: 204/762 - (26%)
• Similarity: 318/762 - (41%)
• Gaps: 144/762 - (18%)

  Fly   154 YNIDPDVEPLRSELQTGKFTILPARTSSGAAIA----------LFTANRHSPLSVSHTTTLQGIV 208
            ||.:....| .|:...|:|.|    ..||::|:          ||..:|.:|::|....|.:..:
Zfish   431 YNEEHTSAP-SSKPPPGRFLI----RDSGSSISITTSTDQPGFLFPVSRTTPITVRRKITEESSL 490

  Fly   209 YQ--LDSALQDSETQRAGL-------------------VFIYDMSGSKYSNFDYDLSQKIL---- 248
            .|  :.:..:.:||:|...                   |:..|:..|..:|....::..:|
Zfish   491 SQPPVQNKSRKNETKRPANRLLPDDSGHFPQSNTVVTDVYYEDVLNSSTTNITPTINNNLLIDQN 555

  Fly   249 ----TLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKALPI 309
                :......||........|......|..||:.. ..:.|...||..            |...
Zfish   556 TEKASTSPPKQPANESSTANATTGSSLSASMKIISQ-TTQPLFNDVFVT------------ATSF 607

  Fly   310 HLGGTLEVDHATWLL-SCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEAATTA 373
            :....|.|..||.|. |..:|.|...:|..|:. ....|.|..|.:|||..:.....|.|...|.
Zfish   608 NNERVLMVSDATSLYESSTRSPTIILEEGSAHF-PPSDGQGEFSGSGSAIFLEELDREWELEQTR 671

  Fly   374 ATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSS 438
            ....:|     |...|  ...|..|...:....:...||:..:|.....::.::.|....:.:..
Zfish   672 MAPKNA-----DPRKT--QEENHEGLPSTFFFESEREASSTYKPQNQDFLSWVTWSAESDSGSGQ 729

  Fly   439 SSSSSAATVANPL-----KLNTSGSADNNSTITNATTAAGAAGAAAGTTTN-------------- 484
            ..|..:.|...|:     |||.  ..:|::..:|::..: ..|...||.|.
Zfish   730 GGSMISQTEDIPIQLIIPKLNI--QEENHAEASNSSPES-RVGMVGGTETEKRAVVPLAIVSTLT 791

  Fly   485 ------------------GGGEFWSENPPSS-ASSGFSDDDSLAGQEGDPKPIDQIVQMVKQ-RG 529
                              ....|:.|:..|: |.|..|....|..::.:..|:...|:.|.. ..
Zfish   792 VLCLVVLVGILIYWRRCFQTAHFYVEDTNSARAISAPSTPLLLPTEDNEALPVKDFVKHVADLHA 856

  Fly   530 RHGLIKEYADIRNRAPEGTFLHARMRA---------NLTKNRYTDVLCYDHSRVVLAH---EDGD 582
            .|...||:..::....|.....|.|..         |.:||||.::|.||||||.|:.   :||
Zfish   857 NHKFSKEFEILKESYEEIQGCTADMGITTDSSNHPDNKSKNRYINILAYDHSRVKLSQNSDKDG- 920

  Fly   583 EPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWE 647
            :..||||||:|||:.|..|||:.||||..:.:|||||||||:..||||.|.::|:||.||.|||
Zfish   921 KTGDYINANYVDGFNQPKAYIAAQGPLKGSLEDFWRMIWEQNVGVIVMITNLVEKGRRKCDQYW- 984

  Fly   648 PTEESSLEFGDYHVRTISVECNEDYMVASLELRNIK--------TDEIRNVSHWQFTSWPDYGVP 704
            |.|... ::|.:.|...|......|.:.:..|||::        ..:.|.|.|:.:|.|||.|||
Zfish   985 PLENQE-DYGCFLVTLKSSRTLAYYTLRTFTLRNVQIKKGSQKGRSQERTVLHFHYTQWPDMGVP 1048

  Fly   705 SSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVG 769
            ...:.:|:|::  ...||:..: :|          |:|||||||:|||||:|.:|..:.::::..
Zfish  1049 EYTLPLLSFIR--TSSQARTAE-MG----------PVVVHCSAGVGRTGTYIVIDSMLKQIKEEN 1100

  Fly   770 TADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDL 816
            |.:|.|.::.||:||.|.:|..:||||.|.||:|...|:..|.:..|
Zfish  1101 TVNIMGFLKHIRTQRNYLVQTEEQYVFIHDALVEAIRSKETLVSSSL 1147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559	31/182 (17%)
		PTPc-N9	529..799	CDD:350391	112/289 (39%)
ptprz1b	XP_073803012.1	None