Protein Alignment Ptpmeg2 and ptpn11b

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001015717.1
• Gene: ptpn11b / 548434
• XenbaseID: XB-GENE-6054495
• Length: 594
• Species: Xenopus tropicalis
• Alignment Length: 316
• Identity: 110/316 - (34%)
• Similarity: 174/316 - (55%)
• Gaps: 35/316 - (11%)

  Fly   527 QRGRHGLIKEYADIRNRAPEGTFLHARMRA----NLTKNRYTDVLCYDHSRVVLAHEDGDEP--- 584
            ::.:.|..:|:..::.:  |...|:.|...    |.:||||.::|.:|.:||.|  .|.||.
 Frog   242 EKAKQGFWEEFEMLQQQ--ECKLLYPRKEGQRPENKSKNRYKNILPFDTTRVTL--RDTDESVAG 302

  Fly   585 SDYINANFVD-------GYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKC 642
            |||||||::.       |.:....||:|||.|..|..|||.|:::::..||||||:.:||.|.||
 Frog   303 SDYINANYIKSTLDEARGSQHYKVYIATQGCLQNTVCDFWAMVYQENTHVIVMTTKEVERSRKKC 367

  Fly   643 GQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLEL-RNIKTDEIRNVSHWQFTSWPDYGVPSS 706
            .:|| |.|..:.::|...|:::.|:..:||::..|:: |..|.:..|.:.|:|:.||||:|||..
 Frog   368 FRYW-PDENCTKDYGCIRVQSLEVQQKKDYILRELQISRMDKVESPRPIWHYQYLSWPDHGVPIE 431

  Fly   707 AMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVG-- 769
            ...:|:||:::...|..:           |...|||||||||||||||.|.:|:.:..:...|
 Frog   432 PGGVLSFLEEINAAQKYI-----------PHSGPIVVHCSAGIGRTGTIIVIDMLVDIINRQGLD 485

  Fly   770 -TADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGM-LQTVDLAGFDERE 823
             ..||..|::.:|.||:..:|...||.|.::|:.:|...|.. |:...:....|||
 Frog   486 CDIDIPKTIQMVRQQRSGMVQTEAQYKFIYMAVQKYIEVRKRHLEEEQMGKLKERE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	103/287 (36%)
ptpn11b	NP_001015717.1	SH2_N-SH2_SHP_like	5..103	CDD:198203
		SH2_C-SH2_SHP_like	111..219	CDD:198185
		PTPc-N11_6	274..523	CDD:350392	100/262 (38%)