Protein Alignment Ptpmeg2 and Ptpro

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_059032.1
• Gene: Ptpro / 50677
• RGDID: 62068
• Length: 1216
• Species: Rattus norvegicus
• Alignment Length: 456
• Identity: 140/456 - (30%)
• Similarity: 209/456 - (45%)
• Gaps: 90/456 - (19%)

  Fly   390 VVTVSNGVGPAGSASGGATT-------------AASAATEPNEN-------------------IT 422
            |||:|: :.||.:.:...|:             .::..||.|.|                   :|
  Rat   777 VVTISS-LLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEVNPNVVVISVLAILSILLIGLLLVT 840

  Fly   423 INGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSAD---NNSTITNATTAAGAAGAAAGTTTN 484
            :..|...|.|.|.     ...|.|..|...|...|...   ..|..|..|.....
  Rat   841 LVILRKKHLQMAR-----ECGAGTFVNFASLEREGKLPYSWRRSVFTFLTLLPSC---------- 890

  Fly   485 GGGEFWSE-------NPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIK---EYAD 539
                .|::       ||       :|.:.....:..:|..:|.....:|...:....|   ::.:
  Rat   891 ----LWTDYLLAFYINP-------WSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEE 944

  Fly   540 IRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYIS 604
            ::....:.....|.:..|..|||||::|.||.|||.|...:.:|.:||||||::.||.....||:
  Rat   945 LKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIA 1009

  Fly   605 TQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECN 669
            ||||||:|..|||:|:.:|...:|||.|:..|:.||||..||..||| .:.:||..|..:|.|..
  Rat  1010 TQGPLPETRNDFWKMVLQQKSRIIVMLTQCNEKRRVKCDHYWPFTEE-PIAYGDITVEMVSEEEQ 1073

  Fly   670 EDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVP--SSAMAMLNFLQKVREKQAQLVQGLGDTW 732
            ||:  ||...|....||.::|.|:.:|:|||:|||  ::|.::|.|:..||: ||...:|
  Rat  1074 EDW--ASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVYTVRQ-QATKSKG----- 1130

  Fly   733 AGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFC 797
                   |:::|||||:|||||||.||..:..:.|....||.|.|.::||.|...:|..:||:|.
  Rat  1131 -------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFI 1188

  Fly   798 H 798
            |
  Rat  1189 H 1189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	109/275 (40%)
Ptpro	NP_059032.1	FN3	434..526	CDD:238020
		FN3	530..630	CDD:238020
		fn3	725..805	CDD:394996	7/28 (25%)
		R-PTPc-O	951..1195	CDD:350462	108/255 (42%)