Protein Alignment Ptpmeg2 and ptprz1a

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_005163194.2
• Gene: ptprz1a / 497461
• ZFINID: ZDB-GENE-090406-1
• Length: 1827
• Species: Danio rerio
• Alignment Length: 912
• Identity: 234/912 - (25%)
• Similarity: 337/912 - (36%)
• Gaps: 266/912 - (29%)

  Fly    18 SGSRSEQDSGCHRRLFLCIAKAVKQFIDLCNNLGANCSTTTATSPSTSSSSASSTQNLIAVVPPQ 82
            |||.| .|..|...|.|.....|...:||..         .::.||....|..|....:...|..
Zfish   739 SGSAS-ADPPCRTTLPLQTLSEVTASVDLMQ---------PSSEPSLLHLSEHSGTISVLSTPAY 793

  Fly    83 LQQLQVQLPAPGGGGGAGAGGGGGGGGGAAPVRRHISHTTAVKFLYARKFDIPRAVSLYEQHEQI 147
            ||.                         :.||.:..|.||.
Zfish   794 LQP-------------------------SVPVSKDYSETTT------------------------ 809

  Fly   148 RLKEYLYNIDPDVEPLRSELQTGKFTILPARTSSGAAIALF--------TANRHSPLSVSHTTTL 204
                   .:|.|.....|   .|:..:|.....|..|...|        ::|...|.|||.....
Zfish   810 -------TLDTDASLSGS---NGESNLLTEWVDSSLAAPTFSSKFSLHASSNSLLPSSVSGLPPC 864

  Fly   205 QGI--------VYQLDSALQDSETQRAGLVFIYDMS----------GSKYSNFDYDLSQKILTLL 251
            ..:        ::|..|:...|....|||    |:|          .:|.|:   |||..:...:
Zfish   865 SSLLSSPVELHLFQSTSSASTSLCSDAGL----DLSTKALLPSLSISTKPSS---DLSLSVAATV 922

  Fly   252 KGGYPARLKKVLIVTAPLWFKA--PFKILRL----------FVREKLRERVFTVSVPQLALHVP- 303
            .....:.:.:.|..:||:...|  |..||.|          .:.........||..|.:...:|
Zfish   923 NNIAQSAIGQSLGASAPIRSSAITPTPILELRSTPTPVVPPTIAPTSPSDSITVVAPVVPPTIPV 987

  Fly   304 -----RKALPIH-LGGTLEVDHATWL--LSCRQSMTNREDELLANIVGVGG---------GSGSG 351
                 ..::|.| ..|..|...:.|.  |...||..:.::.:.|..:....         ..|:.
Zfish   988 SSAPESSSMPTHSADGQQENSASGWTFDLDWGQSSASGDESIAAPYITTASPTEVSPEETDDGNE 1052

  Fly   352 SAAGSAAIVSTNGTETEAATTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATE 416
            ..:.|......||||:|......|:     |...:.|.     .|.|...|.||...|
Zfish  1053 EHSSSFYFEGENGTESEVTDFRVTL-----QPSPSWTL-----RGSGEEESGSGETLT------- 1100

  Fly   417 PNENITINGLSPSHR----------QAANNSSSSSSSAATVANPLKLNTSGSADNNSTITNATTA 471
              :|.|.:..|...|          :.|||||..|          ::..:.|.:...       .
Zfish  1101 --DNETSSDFSIPERTERESEEEPVEDANNSSHES----------RVGLASSIERQK-------K 1146

  Fly   472 AGAAGAAAGTTTNGGGEF-------W-------------SENPPSSASSGFSDDDSLAGQEGDPK 516
            |....|...|.|..|..|       |             |.:|...:||...:...    |.:|.
Zfish  1147 AVVPLAVVSTLTFLGLIFLIGIYIYWRKCFQTAHFYIEDSTSPRVISSSPLLNPTG----EHEPL 1207

  Fly   517 PIDQIVQMVKQRGRHG---------LIKEY--------------ADIRNRAPEGTFLHARMRANL 558
            |:.|.|..|.:  .|.         ::|||              .|..|. |:          |.
Zfish  1208 PVKQFVNHVTE--LHNTSSFSREFEILKEYFEEVQTCTVDLGTTTDCSNH-PD----------NK 1259

  Fly   559 TKNRYTDVLCYDHSRVVLA---HEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMI 620
            .||||.::|.||||||.||   .:||....||||||:|||:.:..|||:.||||..::.|||||:
Zfish  1260 NKNRYVNILAYDHSRVRLAPLNDKDGKSGGDYINANYVDGFNKNKAYIAAQGPLKSSTPDFWRMV 1324

  Fly   621 WEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRN---- 681
            |||:..||||.|.::|:||.||.||| |.|... |:|.:.|...|......|...:..|||
Zfish  1325 WEQNVGVIVMITNLVEKGRKKCDQYW-PLENQE-EYGCFLVTVKSTNVLAYYTKRTFTLRNTSIK 1387

  Fly   682 -----IKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPI 741
                 .:::| |.|:.:.:|.|||.|||...:.:|:|:.|..:.|   ..|:|          |:
Zfish  1388 KGSQRYRSNE-RTVTQYHYTQWPDMGVPEYVLPVLSFVYKSSKAQ---TDGMG----------PM 1438

  Fly   742 VVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY 806
            |||||||:|||||:|.||..:.::::.||.:|.|.::.||:||.|.:|..:||:|.|.||:|...
Zfish  1439 VVHCSAGVGRTGTYIVLDSMLKQIKEKGTVNIMGFLKHIRTQRNYLVQTEEQYIFTHDALVEAIL 1503

  Fly   807 SR 808
            |:
Zfish  1504 SQ 1505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	4/29 (14%)
		SEC14	170..314	CDD:469559	37/188 (20%)
		PTPc-N9	529..799	CDD:350391	115/304 (38%)
ptprz1a	XP_005163194.2	None