Protein Alignment Ptpmeg2 and ptpn11b

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_956748.1
• Gene: ptpn11b / 393426
• ZFINID: ZDB-GENE-040426-1158
• Length: 592
• Species: Danio rerio
• Alignment Length: 294
• Identity: 108/294 - (36%)
• Similarity: 167/294 - (56%)
• Gaps: 30/294 - (10%)

  Fly   527 QRGRHGLIKEYADIRNRAPEGTFLHARMRA----NLTKNRYTDVLCYDHSRVVLAHEDGDEP-SD 586
            ::.:.|..:|:..::.:  |...|:.|...    |..||||.::|.:|.:||.:...|.|.| ||
Zfish   241 EKPKQGFWEEFEVLQQQ--ECKLLYPRKEGQRPENKNKNRYKNILPFDTTRVQIKEADPDVPGSD 303

  Fly   587 YINANFVDGYKQK-------NAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQ 644
            |||||::....::       ..:|:|||.|..|..|||:|:::::..||||||:.|||||.||.:
Zfish   304 YINANYIRSVNEEGRHMDEGKVFIATQGCLQNTVLDFWKMVYQENTHVIVMTTKEMERGRNKCVR 368

  Fly   645 YWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNI-KTDEIRNVSHWQFTSWPDYGVPSSAM 708
            || |...|:.|||...|:.|.....:||:...||:..: :.:..|.:.|:|:.||||:|||:...
Zfish   369 YW-PDLNSTKEFGKVCVKNIEEHTAQDYIRRELEVTRLDRREPPRCIWHYQYLSWPDHGVPNEPG 432

  Fly   709 AMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVG---T 770
            .:|:||::|...|:.:           |...|||||||||||||||.|.:||.|..:...|   .
Zfish   433 GVLSFLEQVNRTQSAI-----------PESGPIVVHCSAGIGRTGTIIVIDILIDIINRQGLDCD 486

  Fly   771 ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY 804
            .||..|::::|.||:..:|...||.|.::|:.:|
Zfish   487 IDIPKTIQRVRQQRSGMVQTEAQYKFIYMAVQQY 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	106/285 (37%)
ptpn11b	NP_956748.1	SH2_N-SH2_SHP_like	5..103	CDD:198203
		SH2_C-SH2_SHP_like	111..218	CDD:198185
		PTPc-N11_6	273..523	CDD:350392	103/260 (40%)