Protein Alignment Ptpmeg2 and PTP-ER

DIOPT Version :9

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Alignment Length: 1063
• Identity: 217/1063 - (20%)
• Similarity: 316/1063 - (29%)
• Gaps: 426/1063 - (40%)

  Fly    53 NCSTTTATSPSTSSSSASSTQNLIAVVPPQLQQLQVQLPAPGGGGGAGAGGGGGGGGGAAPVRRH 117
            :||:||   .|:..|.||.|        |.|...:::......||..     .|.|...||...|
  Fly   420 HCSSTT---QSSLDSDASLT--------PSLGDFELKSACSVDGGSK-----FGIGASLAPRSAH 468

  Fly   118 ----ISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRSELQTGKFTILPAR 178
                :.|:::....     .:|..::|.|....        ...|...|.:.:........|.|:
  Fly   469 KHNQLLHSSSTNLK-----TLPECLTLVEFSSS--------GGGPKESPFKQKSMDLPMPTLQAK 520

  Fly   179 TSSGAAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYD- 242
            |:...:.......|.|    :|:.||     .|.|:..:...           ||..:||:...
  Fly   521 TTVSTSSMNLLQRRGS----NHSLTL-----NLHSSCGNLMN-----------SGLSHSNYSLGS 565

  Fly   243 -LSQKILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKA 306
             |:.|....|..|..::::...:..:.|...:......||.|......:
  Fly   566 ILNSKSSCNLDAGTASQIRADQLPQSHLLGSSQGSRQGLFRRRGSNHSI---------------- 614

  Fly   307 LPIHLGGTLEVDHATWLLSC-----------RQSMTNRED----ELLANIVGVGGGSGS------ 350
                   ||:..|.|  .||           :|:|.:.|.    .:..|..|.|.||||
  Fly   615 -------TLKTGHTT--TSCGDLNSMQQLQQQQAMLSAEKYNRLNMRTNSTGSGSGSGSNVPTPK 670

  Fly   351 -----------------GSAAGSAAIVSTNGTE---TEAATTAATIIS------AVHQLGDNNTT 389
                             ||..|.||     |||   |:......|:.|      |.||....:|.
  Fly   671 RGLLERRGSNQSLTLNMGSILGGAA-----GTEIQMTDIVQPKVTVCSCAAANQAPHQRKFFSTE 730

  Fly   390 VVTVSN-------GVGPAGSASG----------------GATTAASAATEPNENITINGLSPSHR 431
            .:..|.       |....||||.                |||...:...   .||....|||
  Fly   731 NLNSSKANSQKFFGQVCFGSASDLQPNPQQDSVREDQAIGATCTCAGTV---RNIMTRPLSP--- 789

  Fly   432 QAANNS----SSSSSSAATVANPL------KLN--TSGSADNNSTITNATTAAGAAGAAAGTTTN 484
            |..:..    .:|.....:.:|||      :||  ...|...|..|.......|:......|.|:
  Fly   790 QTTSEEFKIYLASIQMLQSASNPLNQFDLIRLNYVFDHSYQTNRNIIEQPPVLGSNARDVETPTD 854

  Fly   485 GGGEFWSENPPSSASSGFSDDDSLAGQE----GDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAP 545
                   ..||||     .|.:.||..:    ...:||.::.:..::|....|.||:.|:.....
  Fly   855 -------MVPPSS-----EDSELLASYQTVVSRMAQPIPELKENEQKRIFRDLHKEFWDLPLNHQ 907

  Fly   546 EGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGD-----------------EPSDYINANFV 593
            |...:.    .:.|||||..:|..::|||:|..|..:                 |...|||||::
  Fly   908 EKPMVF----GSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYI 968

  Fly   594 DG--YKQKNAYISTQGPLPKTSQDFWRMIW---------------------------EQHCLVIV 629
            .|  |..| .|::||||||.|..:||.||:                           :|:...||
  Fly   969 KGPDYVSK-CYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIV 1032

  Fly   630 MTTRVMERGRVKCGQYWEPTE--------------ESSLEFGDYHVRTISVECNEDYMVASLEL- 679
            |.|...|..|.||..|: |.|              :.|....||..|.::.....|.:|||.:.
  Fly  1033 MLTNFTEANRQKCAVYF-PIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAI 1096

  Fly   680 ------RNIKTDE---------------------IRNVS-------------------------- 691
                  |:|..:.                     |:||.
  Fly  1097 DYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASY 1161

  Fly   692 --------HWQFTSWPDYGVPSSAMAMLNFLQKV-----------------REKQAQL------- 724
                    |:.:..|||:..|.....:|:....|                 .|:.|.|
  Fly  1162 HLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEI 1226

  Fly   725 --------VQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRL---------------- 765
                    ||            |..|:||||||||||.|..:...:.:|
  Fly  1227 YQQDIFNAVQ------------PLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSL 1279

  Fly   766 -----------------------------------EDVGT--------------ADIRGTVEKIR 781
                                               |.|.|              .|:.|.|..:|
  Fly  1280 TSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLR 1344

  Fly   782 SQRAYSIQMPDQYVFCHLALIEY 804
            .||...:|..:||...|.|:..|
  Fly  1345 LQRGGMVQNSEQYELIHRAICLY 1367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	5/33 (15%)
		SEC14	170..314	CDD:238099	22/145 (15%)
		Y_phosphatase	557..803	CDD:278528	97/464 (21%)
		PTPc	559..803	CDD:238006	97/462 (21%)
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	96/461 (21%)
		PTPc	917..1364	CDD:238006	96/460 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443560
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19134
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030