Protein Alignment Ptpmeg2 and ptpn4a

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_068079424.1
• Gene: ptpn4a / 368448
• ZFINID: ZDB-GENE-030616-449
• Length: 929
• Species: Danio rerio
• Alignment Length: 603
• Identity: 160/603 - (26%)
• Similarity: 244/603 - (40%)
• Gaps: 158/603 - (26%)

  Fly   280 LFVREKLRERVFTVSVPQLALHVPRKALPIHLGGTLEVDHATWLLSCRQSMTNREDELLANIVGV 344
            |||:|..|.|  ..|:..|..||      ||...:|.|            .:|.:
Zfish   405 LFVQEGPRLR--PSSMGHLVDHV------IHASPSLPV------------FSNHK---------- 439

  Fly   345 GGGSGSGSAAGSAAIVSTNGTE------------TEAATTAATIISAVHQLGDNNTT----VVTV 393
               |.|.:.|.|.::.||...|            ......:..|:|...|..||:..    |.|.
Zfish   440 ---SASSTQANSISLESTPSPEGVEGPPPALPPKQSRKNLSQLILSHSQQDLDNHINEMYDVPTA 501

  Fly   394 SNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGS 458
            ::.|.|.|             ..|::|:.:..:.|...                 .....|..|.
Zfish   502 TDKVMPNG-------------VVPHDNLVLIKMKPDEN-----------------GRFGFNVKGG 536

  Fly   459 ADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDD----------DSLAGQ-- 511
            :|....|..:..|.|.:........|.|.:....|....|.  .|.|          :|.:|:
Zfish   537 SDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGREIAE--HSHDQVVMFIKASCESHSGELI 599

  Fly   512 -----------------------------EGDPKPIDQ-----IVQMVKQRGRHG-LIKEYADIR 541
                                         ..||..:||     .:..:|:....| ::.::..:.
Zfish   600 LLVRPNAIYDVVEEKLETEPDFQYIPEKSPTDPSHLDQDAWRDSMLYLKEGLNSGTILAQFDQLY 664

  Fly   542 NRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVD----GYKQKNAY 602
            .:.|..|...|::..|::||||.|:..||.:||:|   .|.|  ||||||:::    .....|.|
Zfish   665 RKRPGMTMSCAKLPQNISKNRYRDISPYDATRVIL---KGTE--DYINANYINMEIPACSLINRY 724

  Fly   603 ISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVE 667
            |:.|||||.|..|||:|.|||...::||.|..:|||||||.||| |....|..:|.:.:...:.|
Zfish   725 IACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYW-PNPSGSATYGGFQISCQTEE 788

  Fly   668 CNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTW 732
            .|..::|..:.|.:|::.|.|.::..|:.:|||:|||..:...|:|:..||.|:|
Zfish   789 GNSAFLVREITLTHIESGESRELTQIQYLAWPDHGVPDDSTDFLDFVALVRNKRA---------- 843

  Fly   733 AGHPRGPPIVVHCSAGIGRTGTFITLDICISRLE---DVGTADIRGTVEKIRSQRAYSIQMPDQY 794
               .:..|:||||||||||||..||::..:..:|   .|...:|   |..:|.|||..||.|.|:
Zfish   844 ---GKDEPVVVHCSAGIGRTGVLITMETAMCLMECSQPVFPLEI---VRTMRDQRAMMIQTPSQF 902

  Fly   795 VFCHLALIEYAYSRGMLQ 812
            .|...|::: .|..|:::
Zfish   903 KFVCEAILK-VYEEGLVK 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559	12/33 (36%)
		PTPc-N9	529..799	CDD:350391	103/277 (37%)
ptpn4a	XP_068079424.1	B41	30..222	CDD:214604
		FERM_C_PTPN4_PTPN3_like	216..310	CDD:270010
		FA	324..365	CDD:462582
		PDZ_PTPN3-4-like	514..603	CDD:467190	16/107 (15%)
		PTPc-N4	704..915	CDD:350449	88/228 (39%)