Protein Alignment Ptpmeg2 and ptprub

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_009290693.2
• Gene: ptprub / 335096
• ZFINID: ZDB-GENE-030131-7036
• Length: 1450
• Species: Danio rerio
• Alignment Length: 977
• Identity: 211/977 - (21%)
• Similarity: 345/977 - (35%)
• Gaps: 328/977 - (33%)

  Fly    64 TSSSSASSTQNLIAVV---------PPQLQQ-----LQVQLPAPGGGGGAGAGGGGGGGGGAAPV 114
            |.||..|...|...::         ||||.:     |.:||     ...:..|.|        |:
Zfish   262 TQSSRGSGVSNFAELIVKVPPSPIAPPQLLRAGSTYLIIQL-----NTNSILGDG--------PI 313

  Fly   115 RRHISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEY-LYNIDPD------------------- 159
            .|             |:.:...:::.:.:...:.:..| |:::|||
Zfish   314 IR-------------REIEYRASLAPWSEILGVNMVTYKLWHLDPDTEYHISVLLTRPGEGGTGP 365

  Fly   160 -----------VEPLR-------SELQTGKFTI---LPA----------------RTSSGAAIAL 187
                       .||:|       ||:|:.:.|:   :||                .|::|.....
Zfish   366 PGPPLISRTKCAEPMRALRGLRASEIQSRQLTLQWEVPAFNLTRCHTYSVSLCYRYTTAGGGGGH 430

  Fly   188 FTANRHSPLSVSHTT---TLQGI----VYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYDLSQ 245
            .|..|.. |:|.|.|   ||:.:    ..|:..||.::|.::.|                    :
Zfish   431 NTTVREC-LAVEHNTSRFTLRDLPPFHTIQIRLALANTEGKKEG--------------------K 474

  Fly   246 KILTLLKGGYPARLKKVLIVTAPL-------WFKAPFKILRLFVREKLRERVFTVSVPQLALHVP 303
            :::...:...|..:....:...||       | :.|.:...|..:.::..:....|.|.:.:..|
Zfish   475 EVMFQTEEDIPGGIAPESLTFTPLEDMIFLKW-EEPVEPNGLITQYEISYQSIESSDPGINVPGP 538

  Fly   304 RKAL------PIHLGGTLEVDHATWLLSCR---------QSMTNREDELLANI------------ 341
            |:.:      ..|:...|. ...|:|:|.|         .::|    |:..||
Zfish   539 RRTVSKLKNETYHMFSNLH-PGTTYLISVRARTAKGFGQTALT----EITTNISAPTFDYGDMPS 598

  Fly   342 ----------VGVGGGSGSGSAAGSAAIVSTNGTETEAATTAATIISAVHQLGDNNTTVVTVSNG 396
                      |.:....|.|:...:..:|    .|.||..      ....:||..:...:..|:|
Zfish   599 PLSETENTITVLLRPAQGRGAPVSTYQVV----VEEEAGR------KVKRELGIQDCFPIPTSHG 653

  Fly   397 VGPAGSASGGAT-----TAASAAT--EPNENITING-----LSPSHRQAANNSSSSSSSAATVAN 449
            ...|..|....|     ::.|.||  ...:|.|.||     |.|.........:.|:....|..|
Zfish   654 EAQARGAPHYYTAELPPSSLSEATPFTVGDNHTYNGYWNSPLDPRKNYLVYFQAMSNFRGETRIN 718

  Fly   450 PLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNG-----------------GGEFWS------ 491
            .:::....:..::......|..:...|...|....|                 |.:::|
Zfish   719 CIRIARKAACKDHQRALEVTQRSEEMGLILGVCAGGLVVLILLLGAIIIIIKKGRDYYSYSYYPR 783

  Fly   492 ----------------ENPPSSASSGFSDDDSL-------------------------------- 508
                            .|...|....|:|..:|
Zfish   784 KPGNMNKTPITYRQEKSNMMGSMERSFTDQSTLQEDERMALSFMDTHTCSTRSDPRSSMNESSSL 848

  Fly   509 --------AGQEGDPKPIDQI------------VQMVKQRGRHGLIKEYA------DIRNRAPEG 547
                    .|::|.|....|:            :..:|....:|..:||.      ||..:..:
Zfish   849 LGGSPRRQCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFDGWDINKKKDK- 912

  Fly   548 TFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVD------GYKQKNAYISTQ 606
                       ||.|:..::.||..||.|....||..|||||||::|      ||.:.|.:|:||
Zfish   913 -----------TKGRHDTLMGYDRHRVKLHPLLGDPNSDYINANYIDIRINREGYHRSNHFIATQ 966

  Fly   607 GPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNED 671
            ||..:|..|||||:|:::|..|||.|:::|.|||||.:||  .:||.: :||..:..:..|...:
Zfish   967 GPKQETVYDFWRMVWQENCFSIVMITKLVEVGRVKCCKYW--PDESEM-YGDIKITLLKTETLAE 1028

  Fly   672 YMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHP 736
            |.|.:..|..........|..:.|||||::|||..|..:|.|:::|: ....|..|
Zfish  1029 YTVRTFALERRGYSAKHEVCQFHFTSWPEHGVPYHATGLLAFIRRVK-TSTPLDAG--------- 1083

  Fly   737 RGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLAL 801
               |:|||||.|.||||.:|.||:.:...|..|..||...|:.:.|:|...||..:||:|.|.|:
Zfish  1084 ---PVVVHCSVGAGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRINMIQTEEQYIFIHDAI 1145

  Fly   802 IE 803
            :|
Zfish  1146 LE 1147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	2/29 (7%)
		SEC14	170..314	CDD:469559	29/182 (16%)
		PTPc-N9	529..799	CDD:350391	100/281 (36%)
ptprub	XP_009290693.2	None