Protein Alignment Ptpmeg2 and ptpn11a

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_956140.1
• Gene: ptpn11a / 333979
• ZFINID: ZDB-GENE-030131-5911
• Length: 594
• Species: Danio rerio
• Alignment Length: 335
• Identity: 123/335 - (36%)
• Similarity: 180/335 - (53%)
• Gaps: 58/335 - (17%)

  Fly   525 VKQRGRHGLIKEYADIRNRAPEGTFLHARMRA----NLTKNRYTDVLCYDHSRVVLAHEDGD--- 582
            |||    |..:|:..::.:  |...|::|...    |..||||.::|.:||:||||.  |||
Zfish   244 VKQ----GFWEEFETLQQQ--ECKLLYSRKEGQRPENKNKNRYKNILPFDHTRVVLT--DGDVNE 300

  Fly   583 EPSDYINANFV--------DGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGR 639
            :.|||||||.:        :..|.|.:||:|||.|..|..|||||:::::..||||||:.:|||:
Zfish   301 QGSDYINANLIMPDNEAKSNNSKLKRSYIATQGCLQNTISDFWRMVFQENSRVIVMTTKEVERGK 365

  Fly   640 VKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNI-KTDEIRNVSHWQFTSWPDYGV 703
            .||.:|| |...:..|:|...||.:......||::..|:|..: :.:..|.|..:.|.:|||:||
Zfish   366 SKCVKYW-PDVSALKEYGAMRVRNVKETMAHDYILRELKLSKVGQGNTERTVWQYHFRAWPDHGV 429

  Fly   704 PSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDV 768
            |.....:|:||::|:.||.      |.|.||     |||||||||||||||||.:||.|..:.:.
Zfish   430 PGDPGGVLDFLEEVKLKQE------GITGAG-----PIVVHCSAGIGRTGTFIVIDILIDIIREK 483

  Fly   769 GT---ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY-------------------AYSRGML 811
            |.   .|:..|::.:||||:..:|...||.|.::|:..|                   .|:....
Zfish   484 GVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKIKGREYTNIKY 548

  Fly   812 QTVDLAGFDE 821
            ...||:|.|:
Zfish   549 SLSDLSGGDQ 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	113/288 (39%)
ptpn11a	NP_956140.1	SH2_N-SH2_SHP_like	5..103	CDD:198203
		SH2_C-SH2_SHP_like	111..219	CDD:198185
		PTPc-N11	273..525	CDD:350453	110/265 (42%)