Protein Alignment Ptpmeg2 and Ptp4E

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_525076.2
• Gene: Ptp4E / 31425
• FlyBaseID: FBgn0004368
• Length: 1767
• Species: Drosophila melanogaster
• Alignment Length: 824
• Identity: 203/824 - (24%)
• Similarity: 330/824 - (40%)
• Gaps: 193/824 - (23%)

  Fly   107 GGGGAAPVRR----H---ISHTTAVKFLYARK--------------FDIPRAVSLYEQHEQIRLK 150
            ||..:.||:|    |   ||...|:: :.||:              |:: :.:|..|:..|: |:
  Fly   885 GGVASLPVQRLYRLHPLPISDLKAIQ-VAAREITLHWTAPAGEYTDFEL-QYLSADEEAPQL-LQ 946

  Fly   151 EYLYNIDPDVEPLRSELQTGKFTILPARTSS-----GAAIALFTANRHS-PLSVSHTTTLQGIVY 209
            ....|.:..::.|| ......||:: .|:.|     .|.:::.|..|.| |:|.|: .||.....
  Fly   947 NVTKNTEITLQGLR-PYHNYTFTVV-VRSGSIQGTDFADVSVSTLMRSSAPISASY-QTLTAPPG 1008

  Fly   210 QLDSALQDSETQRAGLVFIYDMS-GSKYSNFDY------------DLSQ----------KILTLL 251
            ::| ..|.|:.|...:.|.:.:. ..::...||            |:|.          ||..|:
  Fly  1009 KVD-YFQPSDVQPGEVTFEWSLEPAEQHGPIDYFRITCQNADDAADVSSYEFPVNATQGKIDGLV 1072

  Fly   252 KGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKL---RERVFTVSVPQLALHVPRKAL-PIHL- 311
            .|.:                    .|.|:..:..|   .||....::|.||..||..:: |:.:
  Fly  1073 PGNH--------------------YIFRIQAKSALGYGAEREHIQTMPILAPPVPEPSVTPLEVS 1117

  Fly   312 --GGTLEVDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGS-------------AAI-- 359
              ..|:|:.......|....|......::|..|   |.:.||....|             .||
  Fly  1118 RTSSTIEISFRQGYFSNAHGMVRSYTIIIAEDV---GKNASGLEMPSWQDVQAYTVWLPYQAIEP 1179

  Fly   360 ----VSTNGTETEAAT----TAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGAT--TAASAA 414
                :::||:...:..    |..|.....||.|..|             |....|.|  ....|.
  Fly  1180 YNPFLTSNGSRKSSLEAEHFTIGTANCDKHQAGYCN-------------GPLRAGTTYRIKIRAF 1231

  Fly   415 TEPNENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAA 479
            |:.::.......||...:.::....:::.:|.:...:.|...........|..|:..|......|
  Fly  1232 TDEDKFTDTVYSSPITTERSDTVIVAATVSAVLLVAMVLVVVYCQHRCQLIRRASKLARMQDELA 1296

  Fly   480 GTTTNGGGEFWSENPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRA 544
            .....    :.:.|.|..... ||:...:...:.|.:                ..:|:.::::..
  Fly  1297 ALPEG----YITPNRPVHVKD-FSEHYRIMSADSDFR----------------FSEEFEELKHVG 1340

  Fly   545 PEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPL 609
            .:.....|.:..|..|||:|::|.|||||..|...|.|:.|||||||::.|:.....:|.|||||
  Fly  1341 RDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPL 1405

  Fly   610 PKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGD----------YHVRTI 664
            ..|.::||||.||.:...|||.||..|:||.||.||| |.:..::.:||          ||..:|
  Fly  1406 HSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYW-PVDRVAMFYGDIKVQLIIDTHYHDWSI 1469

  Fly   665 SVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLG 729
            |     ::||:    ||.   |.|.:.|:.||:|||:|||....:::.|::..|:.       :|
  Fly  1470 S-----EFMVS----RNC---ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDV-------IG 1515

  Fly   730 DTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQY 794
            ....      ||:||||||:||:||||.||..:..:......||.|.|..:|.:|.:.:|...||
  Fly  1516 TDMR------PIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQY 1574

  Fly   795 VFCHLALIEYAYSRGMLQTVDLA-----GFD------EREPDSE 827
            |..|..|:.....:..|....|.     |::      ||:|.::
  Fly  1575 VCIHQCLLAVLEGKEHLLADSLELHANDGYEVTKIYLERQPQTK 1618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	11/50 (22%)
		SEC14	170..314	CDD:469559	37/179 (21%)
		PTPc-N9	529..799	CDD:350391	101/279 (36%)
Ptp4E	NP_525076.2	FN3	<94..>334	CDD:442628
		fn3	247..328	CDD:394996
		FN3	319..>749	CDD:442628
		fn3	708..796	CDD:394996
		fn3	902..978	CDD:394996	17/80 (21%)
		fn3	1013..1092	CDD:394996	15/98 (15%)
		PTP_tm	1127..1247	CDD:465889	25/135 (19%)
		R3-PTPc	1358..1579	CDD:350396	96/246 (39%)