Protein Alignment Ptpmeg2 and Ptprj

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_038960584.1
• Gene: Ptprj / 29645
• RGDID: 3454
• Length: 1352
• Species: Rattus norvegicus
• Alignment Length: 829
• Identity: 199/829 - (24%)
• Similarity: 319/829 - (38%)
• Gaps: 258/829 - (31%)

  Fly   153 LYNID--PDVEPLRSELQTGKFTILPARTSSGAAIALFT-ANRHSPLSVSHTTTLQGIVYQ-LDS 213
            |||:.  |:|:.:.               .:.::|..:| .:..|.:.|:..||:..|.:: ||:
  Rat   617 LYNVTIFPEVDQME---------------GNSSSITQYTRPSNVSYIEVNTNTTVAAIQWKNLDA 666

  Fly   214 ALQDSETQRAGLVFIYDMSGSKYSNFDYDLSQKILTLLKGG----YPARLKKVLIVTAPLWFKAP 274
            |                     .:::.|.     :.:||.|    ..:|::.:..||.|......
  Rat   667 A---------------------SASYSYS-----VLILKAGDGSNVTSRVRDIPSVTIPGLIPGV 705

  Fly   275 FKILRLFVREKLR----------ERVFTVSVPQL-ALH---VPRK-------ALP--IHLGGTLE 316
            ...:::|.  |:|          :::|.:...|: :||   ||::       |.|  ::.|..|.
  Rat   706 SYEVKIFT--KIRNTEVGNEVPGQKLFCMEPAQVDSLHCEVVPKEPALVLKWACPPGMNSGFELG 768

  Fly   317 VDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEAATTAATIISAVH 381
            |....|     .:||:.|:..|.|                         :||..|.    ::.::
  Rat   769 VRSDAW-----DNMTHLENCTLDN-------------------------DTECRTE----VTYLN 799

  Fly   382 QLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEP-----NENITINGLSPSHRQAANNSSSSS 441
            .....|.::.|:|.|    ..|....:|..:..|:|     :.|||    |.||.......|...
  Rat   800 FSTSYNISIATLSCG----KMALPTQSTCTTGITDPPPPDGSPNIT----SVSHNSVKVKFSGFE 856

  Fly   442 SSAATVANPLKLNTSGSADNNST------------------------------------------ 464
            :|...:.....|.|:|.|...||
  Rat   857 ASHGPIKAYAVLLTTGEAGQPSTDVLKYTYEDFKKGASDTYVTYLIRIEEKGQSQGLSEALNYEI 921

  Fly   465 -ITNATTAAG-----------AAGAAAGTTT-----------NGGGEFWSENPPSSASSGFSDDD 506
             :.|.:|..|           .....||.|.           ||...:.|.:|.|.|.|...|..
  Rat   922 DVGNQSTTLGYYNGRLEPLGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVSLPQDPG 986

  Fly   507 SLAG-----------------------QEGDPKPIDQIVQMVKQR-------------------- 528
            .:.|                       :..|.|..:.....:|.:
  Rat   987 VICGAVFGCIFGALAIVAVGGFIFWRKKRKDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQAD 1051

  Fly   529 GRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFV 593
            ...|..:||.|::..........|.:..|..||||.:||.||.|||.|:.:. ....||||||::
  Rat  1052 SNCGFAEEYEDLKLIGISLPKYAAEIAENRGKNRYNNVLPYDISRVKLSVQT-HSTDDYINANYM 1115

  Fly   594 DGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGD 658
            .||..|..:|:||||||.|.:|||||:||::...|||.|:.:|:||.||.:|| |::::. ::||
  Rat  1116 PGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYW-PSKQAQ-DYGD 1178

  Fly   659 YHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQ 723
            ..|...|.....::.:....::|:::.|...:..:.||||||:|||.:...::||...||:...|
  Rat  1179 ITVAMTSEVVLPEWTIRDFVVKNMQSSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQ 1243

  Fly   724 LVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSI 788
            :           |...||:||||||:|||||||.:|..|.::|:..|.|:.|.|..:|..|...:
  Rat  1244 I-----------PPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMV 1297

  Fly   789 QMPDQYVF---CHLALI--------EYAYSRGMLQTVDLAGFDEREPDS 826
            |..|||||   |.|.:|        :..|......|:    ::..||.|
  Rat  1298 QTEDQYVFLNQCVLDIIRAQKDSKVDLIYQNTTAMTI----YENLEPVS 1342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559	30/172 (17%)
		PTPc-N9	529..799	CDD:350391	106/272 (39%)
Ptprj	XP_038960584.1	FN3	169..659	CDD:442628	11/56 (20%)
		fn3	642..719	CDD:394996	19/104 (18%)
		PTP_tm	850..980	CDD:465889	20/129 (16%)
		R-PTPc-J	1084..1312	CDD:350463	99/241 (41%)