Protein Alignment Ptpmeg2 and Ptpn22

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001099930.1
• Gene: Ptpn22 / 295338
• RGDID: 1307992
• Length: 804
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 104/325 - (32%)
• Similarity: 157/325 - (48%)
• Gaps: 45/325 - (13%)

  Fly   511 QEGDPKPI------DQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCY 569
            :|...|.|      ::.:::.:|..::...|.|.....:.|:          |:.||||.|:|.|
  Rat    12 KEAQKKKINREEFANEFLKLKRQSTKYKADKIYPTTVAQRPK----------NIKKNRYKDILPY 66

  Fly   570 DHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRV 634
            |||.|.|:....||.|.||||:|:.|.....|||:|||||..|..||||||||...|||||....
  Rat    67 DHSLVELSLLTSDEDSSYINASFIKGVYGPRAYIATQGPLSTTLLDFWRMIWEYRVLVIVMACME 131

  Fly   635 MERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIK---TDEIRNVSHWQFT 696
            .|.|:.||.:||....|:.|:||.:     |:.|..:...:..::|.:|   ..|.|.|..:.:.
  Rat   132 FEMGKKKCERYWAEPGETQLQFGPF-----SISCETEKKKSDYKIRTLKAKFNSETRIVYQFHYK 191

  Fly   697 SWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDIC 761
            :|||:.||||...:|..:..:|..|..      |.       .|:.:|||||.||||....:|..
  Rat   192 NWPDHDVPSSIDPILQLIWDMRCYQED------DC-------VPLCIHCSAGCGRTGVICAVDYT 243

  Fly   762 ISRLED---VGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDLAGFDERE 823
            ...|:|   .....:...::::|:||...:|..:||...:.|::|.     ..:.||:...:.||
  Rat   244 WMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVLEL-----FKRHVDIISDNHRE 303

  Fly   824  823
              Rat   304  303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	94/275 (34%)
Ptpn22	NP_001099930.1	PTPc-N22	57..290	CDD:350450	92/255 (36%)
		Herpes_BLLF1	<539..800	CDD:282904