Protein Alignment Ptpmeg2 and Ptpn9

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001013058.1
• Gene: Ptpn9 / 266611
• RGDID: 628726
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 695
• Identity: 272/695 - (39%)
• Similarity: 362/695 - (52%)
• Gaps: 156/695 - (22%)

  Fly   118 ISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRSELQTGKFTILPARTSSG 182
            :|...|||||.|||||:.|||.|:..:.:.|.||.:..:.|..||||||:.:||||||..|..:|
  Rat    42 LSWNVAVKFLMARKFDVLRAVELFHCYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTG 106

  Fly   183 AAIALFTANRHSP-LSVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYDLSQK 246
            |:||||||..|.| .||.| ..||.:.|.||.|:...||||.||||||||.||.|:||:.||.:|
  Rat   107 ASIALFTARLHHPHKSVQH-VVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKK 170

  Fly   247 ILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKALPIHL 311
            :|.||||.:||||||||||.||:||:.|:.|:.|.:::|:|||:..:...::..|:||:.||.:|
  Rat   171 VLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENL 235

  Fly   312 GGTLEVDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEAATTAATI 376
            ||.:::|.|||
  Rat   236 GGYIKIDLATW------------------------------------------------------ 246

  Fly   377 ISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSSSSS 441
                      |...:...||                 ..:|.:.|.:..|.|:
  Rat   247 ----------NFQFLPQVNG-----------------HPDPFDEIILFSLPPA------------ 272

  Fly   442 SSAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDD 506
                                                                         .|.|
  Rat   273 -------------------------------------------------------------LDWD 276

  Fly   507 SLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDH 571
            |:.........|.::|..|..|.:.|:.:||.|||...|.|||..:....||.||||.||.|.|.
  Rat   277 SVHVPGPHAMTIQELVDYVNTRQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQ 341

  Fly   572 SRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVME 636
            :||.|....|...:|||||:|:||||||||||.|||||..|.:|||.|:|||..||||||||..|
  Rat   342 TRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEE 406

  Fly   637 RGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDY 701
            .||.||||||...::|.::||...|..:.||....|...:||:.|.:..:.|.|:|:||.|||||
  Rat   407 GGRRKCGQYWPLEKDSRIQFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDY 471

  Fly   702 GVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLE 766
            ||||||.::::||:.||.:|:..|..||....|....|||||||||||||||||.:||||:::||
  Rat   472 GVPSSAASLIDFLRVVRSQQSMAVGSLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLE 536

  Fly   767 DVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGML 811
            ::||.::..||.::|:|||:|||.|:||.||:.|::|:|...||:
  Rat   537 ELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMV 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	15/25 (60%)
		SEC14	170..314	CDD:469559	79/144 (55%)
		PTPc-N9	529..799	CDD:350391	144/269 (54%)
Ptpn9	NP_001013058.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		CRAL_TRIO_N	20..66	CDD:215024	15/23 (65%)
		SEC14	90..238	CDD:214706	80/148 (54%)
		PTPc-N9	299..569	CDD:350391	144/269 (54%)